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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> IL6R抗體
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更新時(shí)間:2018-01-04 16:52:55瀏覽次數(shù):874次
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抗原
Interleukin-6 Receptor (IL6R)
別名 IL6R, il-6ra, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80, IL6R1, Il6ra, IL-6Ralpha, IL-6R, Il6r
抗原表位
其他選擇 AA 1-365
AA 1-365(7),AA 44-357 (6),Extracellular Domain (5),Internal Region (4),AA 1-468 (3),AA 21-120 (3),AA 216-356 (2),AA 385-462 (2),AA 19-108 (1),AA 192-458 (1),AA 20-339 (1),AA 20-364 (1),AA 205-347 (1),AA 21-121 (1),AA 23-617 (1),AA 246-260 (1),AA 52-204 (1),Isoform 1 (1)
適用
其他選擇 Human
Human(70),Murine (42),Rat ((Rattus)) (19)
宿主
其他選擇 Rabbit
Rabbit(56),Mouse (44),Rat (14),Goat (5)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(11),FITC (6),PE (4),APC (3),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin,His tag,S tag (1),CF (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),HRP (1),His tag,GST tag (1),His tag,T7 tag (1)
zui低檢測(cè)濃度 0.16 ng/well
應(yīng)用范圍
其他選擇 ELISA
ELISA(57),Western Blotting (WB) (50),Flow Cytometry (FACS) (41),Immunohistochemistry (Frozen Sections) (IHC (fro)) (22),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16),Immunocytochemistry (ICC) (13),Immunohistochemistry (IHC) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Functional Studies (Func) (6),Immunoprecipitation (IP) (6),Neutralization (Neut) (6),Enzyme Immunoassay (EIA) (4),Immunoassay (IA) (3),Immunofluorescence (IF) (2),Blocking Antibody (Inhibition) (1),ELISA (Capture) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國(guó) (更改)
IL6R抗體
產(chǎn)品細(xì)節(jié)
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產(chǎn)品細(xì)節(jié)
顯示 隱藏
亞型 IgG
特異性 Human IL6R / CD126
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human IL6 receptor extracellular domain (rhIL6R, NP_000556.1, Met 1-Pro 365). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered
目標(biāo)詳細(xì)情況
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目標(biāo)詳細(xì)情況
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別名 IL6R
背景 Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (sIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a sIL-6R protein are able to mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signalling. Through this so-called 'trans-signalling' mechanism, IL-6 is able to stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and sIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.
NCBI Accession NP_000556.1
研究領(lǐng)域 Stem Cells, Hematopoietic Progenitors, Innate Immunity, Cytokines, Immunology
使用細(xì)節(jié)
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使用細(xì)節(jié)
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應(yīng)用備注 ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human IL6R. The detection limit for Human IL6R is approximay 0.16 ng/well.
限制 For Research Use only
貯存及處理
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貯存及處理
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緩沖液 PBS with 5% trehalose
儲(chǔ)存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months
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