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LAMP3 抗體

抗原
Lysosomal-Associated Membrane Protein 3 (LAMP3)
別名 DC-LAMP, CD208, DC LAMP, DCLAMP, LAMP, LAMP-3, TSC403, 1200002D17Rik, Cd208
抗原表位
其他選擇 AA 28-381
N-Term(12),AA 16-45 (8),AA 28-381 (7),Internal Region (4),AA 8-38 (2),AA 1-416 (1),AA 116-372 (1),AA 274-323 (1)
適用
其他選擇 Human
Human(96),Murine (45),Bovine (12),Rat ((Rattus)) (12),Cat (10),Dog (Canine) (10),Sheep (Ovine) (10)
宿主
其他選擇 Rabbit
Rabbit(50),Mouse (34),Rat (20),Goat (2)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(12),Alexa Fluor 488 (11),Alexa Fluor 647 (11),Alexa Fluor 546 (10),FITC (2),HRP (2),PE (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 555 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
zui低檢測濃度 0.0049 ng/well
應(yīng)用范圍
其他選擇 ELISA
Flow Cytometry (FACS)(37),Western Blotting (WB) (37),Immunohistochemistry (Frozen Sections) (IHC (fro)) (34),ELISA (27),Immunohistochemistry (IHC) (18),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunofluorescence (IF) (8),Immunocytochemistry (ICC) (5),Enzyme Immunoassay (EIA) (1),Immunoassay (IA) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)

LAMP3 抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
亞型 IgG
特異性 Human CD208 / LAMP3 / DC-LAMP
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human CD208 / LAMP3 (rh LAMP3, NP_055213.2, Lys 28-Thr 381). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 LAMP3
背景 Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.
NCBI Accession NP_055213.2
研究領(lǐng)域 Stem Cells, Hematopoietic Progenitors, Organelles

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1.0 μg/mL This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human LAMP3. The detection limit for Human LAMP3 is 0.0049 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項 Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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