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CX3CL1抗體

抗原
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1)
別名 CX3CL1, DKFZp459K117, Cx3C-rs1, Scyd1-rs1, Cx3c, Scyd1, AB030188, ABCD-3, AI848747, CX3C, Cxc3, D8Bwg0439e, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin
抗原表位
其他選擇 AA 1-339
N-Term(15),AA 1-339 (7),Internal Region (6),AA 20-150 (5),AA 379-397 (2),AA 1-363 (1),AA 201-250 (1),AA 25-332 (1),AA 25-337 (1),AA 25-339 (1),AA 26-135 (1),AA 26-136 (1),AA 81-337 (1),AA 81-341 (1),C-Term (1),Intracellular (1),Middle Region (1)
適用
其他選擇 Human
Human(101),Murine (39),Rat ((Rattus)) (25)
宿主
其他選擇 Rabbit
Rabbit(97),Mouse (8),Goat (4),Chicken (2),Guinea Pig (1),Rat (1),Sheep (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(11),HRP (3),FITC (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1),PE (1)
zui低檢測(cè)濃度 0.0195 ng/well
應(yīng)用范圍
其他選擇 ELISA
Western Blotting (WB)(90),ELISA (48),Immunohistochemistry (IHC) (28),Immunoprecipitation (IP) (19),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13),Flow Cytometry (FACS) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunocytochemistry (ICC) (8),Immunohistochemistry (Frozen Sections) (IHC (fro)) (7),Enzyme Immunoassay (EIA) (5),Immunofluorescence (IF) (3),Functional Studies (Func) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Blocking Antibody (Inhibition) (1),Dot Blot (DB) (1),Immunoassay (IA) (1),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1),Neutralization (Neut) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國(guó) (更改)

CX3CL1抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
亞型 IgG
特異性 Human CX3CL1 / FKN
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human CX3CL1 extracellular domain (rhCX3CL1, NP_002987.1, Met 1-Arg 339). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 CX3CL1
背景 Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines.
NCBI Accession NP_002987.1
研究領(lǐng)域 Cardiovascular, Atherosclerosis, Innate Immunity, Chemokines

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CX3CL1. The detection limit for CX3CL1 is approximay 0.0195 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲(chǔ)存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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