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BAMBI抗體

抗原
BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI)
別名 NMA, nma, BAMBI, Zfnma, bambi, cb998, fc44c12, id:ibd5020, wu:fc44c12, wu:fe01e03, 2610003H06Rik
抗原表位
其他選擇 AA 1-152
AA 1-152(7),AA 1-260 (1),AA 1-261 (1)
適用
其他選擇 Human
Human(26),Murine (15),Rat ((Rattus)) (15),Bovine (13),Dog (Canine) (13)
宿主
其他選擇 Rabbit
Rabbit(21),Mouse (5)
克隆類(lèi)型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
PE(2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
zui低檢測(cè)濃度 0.00975 ng/well
應(yīng)用范圍
其他選擇 ELISA
Flow Cytometry (FACS)(12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),ELISA (9),Western Blotting (WB) (8),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國(guó) (更改)

BAMBI抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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亞型 IgG
特異性 Human BAMBI / NMA
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human BAMBI (rh BAMBI, NP_036474.1, Met 1-Ala 152). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過(guò)濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 BAMBI
背景 BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellular domain and a short cytoplasmic region that share sequence similarities with type 1 receptors, whose members have functions in signal transduction in various developing and pathological processes. BAMBI competes with the type 1 receptor, a receptor of the transforming growth factor-beta (TGF-beta), through functioning as negative regulators of TGF- beta by limiting the signaling range of the TGF-beta family during early embryogenesis. The expression of BAMBI can be induced by accumulated beta-catenin and BMP. The expression level of BAMBI was found aberrantly elevated in most colorectal and hepatocellular carcinomas relative to the corresponding non-cancerous tissues. It suggestes that beta-catenin and TGF-beta interfere growth arrest by inducing the expression of BAMBI, and this may contribute to colorectal and hepatocellular tumorigenesis.
NCBI Accession NP_036474.1
研究領(lǐng)域 Stem Cells

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human BAMBI. The detection limit for Human BAMBI is 0.00975 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲(chǔ)存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 monthsxy-15208R C5orf495號(hào)染色體開(kāi)放閱讀框49抗體
xy-15203R C5orf355號(hào)染色體開(kāi)放閱讀框35抗體
xy-13856R CEP192中心體蛋白192抗體
xy-13857R CEP27中心體蛋白27抗體
xy-13858R CEP290中心體蛋白290抗體
xy-13859R CEP63中心體蛋白63抗體
xy-13860R CEP70中心體蛋白70/p10結(jié)合蛋白抗體
xy-13861R CEP72中心體蛋白72抗體
xy-13865R CEP95中心體蛋白95抗體
xy-13864R CEP89中心體蛋白89抗體
xy-13866R CERD4CERD4蛋白抗體
xy-13867R CES1P1CES1P1蛋白抗體
xy-13868R CES2羧酸酯酶2抗體
xy-13869R CES3羧酸酯酶3抗體
xy-13870R CES4A羧酸酯酶4A抗體
xy-13871R CES6羧酸酯酶6抗體
xy-13872R CezanneCezanne蛋白抗體
xy-13873R CFC1內(nèi)臟移位線管蛋白CFC1蛋白抗體
xy-13874R CFHL2補(bǔ)體因子H相關(guān)蛋白2抗體
xy-13875R CFHL4補(bǔ)體因子H相關(guān)蛋白4抗體
xy-13876R CFHL5補(bǔ)體因子H相關(guān)蛋白5抗體
xy-13877R CG028/C7orf28A7號(hào)染色體開(kāi)放閱讀框28A抗體
xy-13878R CGBPCpG結(jié)合蛋白抗體
xy-13879R CGGBP1CGG結(jié)合蛋白1抗體
xy-13880R CGK2cGMP依賴(lài)性蛋白激酶2抗體
xy-13881R CGNL1結(jié)蛋白樣蛋白CGNL1抗體
xy-13882R CGREF1細(xì)胞生長(zhǎng)調(diào)節(jié)蛋白CGREF1抗體
xy-13884R CHAD富含亮氨酸軟骨蛋白抗體
xy-13885R CHADL軟骨蛋白樣蛋白抗體
xy-13887R CHCHD3卷曲螺旋結(jié)構(gòu)域蛋白CHCHD3抗體