CD5抗體 返回列表頁(yè)

CD5抗體

抗原
CD5 Molecule (CD5)
別名 CD5, Ly-1, Ly-12, Ly-A, Lyt-1, LEU1, T1
抗原表位
其他選擇 AA 1-372
C-Term(11),AA 1-371 (10),Internal Region (9),AA 1-372 (7),AA 202-232 (7),pTyr453 (7),Tyr453 (6),AA 403-495 (3),Cytoplasmic Domain (3),Intracellular (3),N-Term (3),AA 27-233 (2),Leu1 (2),AA 25-368 (1),AA 375-425 (1),AA 421-470 (1),AA 445-495 (1),AA 46-360 (1),AA 50-100 (1),Center (1),Ser213 (1),Val449 (1)
適用
其他選擇 Human
Human(376),Murine (192),Rat ((Rattus)) (92),Bovine (36),Cat (32),Chicken (25),Pig (Porcine) (17),Dog (Canine) (13),Sheep (Ovine) (9),Goat (1),Monkey (1)
宿主
其他選擇 Rabbit
Mouse(420),Rabbit (125),Rat (125)
克隆類(lèi)型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
FITC(116),PE (90),Biotin (75),APC (29),Allophycocyanin (5),SPRD (5),Cy7,PE (3),HRP (3),PerCP (3),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),PerCP,Cy5.5 (2),Alkaline Phosphatase (AP) (1),DyLight 488 (1),DyLight 550 (1),DyLight 594 (1),DyLight 650 (1),DyLight 680 (1),DyLight 755 (1),PE,Cy7 (1)
zui低檢測(cè)濃度 0.00245 ng/well
應(yīng)用范圍
其他選擇 Western Blotting (WB), ELISA
Flow Cytometry (FACS)(491),Western Blotting (WB) (138),Immunoprecipitation (IP) (102),Immunohistochemistry (IHC) (88),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (84),Immunohistochemistry (Frozen Sections) (IHC (fro)) (82),ELISA (54),Immunofluorescence (IF) (43),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (20),Immunocytochemistry (ICC) (15),Functional Studies (Func) (13),Cytotoxicity Test (CyTox) (11),Immunohistochemistry (Acetone-fixed) (IHC (af)) (11),Mass Cytometry (CyTOF) (6),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (5),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Blocking Reagent (BR) (1),Fluorescence Microscopy (FM) (1),Immunoassay (IA) (1),Immunostaining (IS) (1)
規(guī)格 100 μg
發(fā)貨至 中國(guó) (更改)

CD5抗體

產(chǎn)品細(xì)節(jié)

圖像 貯存及處理 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁(yè)首

產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Recombinant Human CD5 protein
亞型 IgG
特異性 Human CD5
產(chǎn)品特性 Produced in rabbits immunized with purified, human cell-derived, recombinant Human CD5 (rh CD5, NP_055022.2, Met 1-Pro 372). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過(guò)濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

圖像 貯存及處理 使用細(xì)節(jié) 回頁(yè)首

目標(biāo)詳細(xì)情況

顯示 隱藏
別名 CD5
背景 T-cell surface glycoprotein CD5, also known as Lymphocyte antigen T1 and LEU1, is a single-pass type I membrane protein. CD5 contains 3 SRCR domains and has been regarded as a possible B cell lineage marker differentiating subsets, CD5+ B cells (also termed B1 cells) and conventional B cells (or B2 cells). CD5 is expressed at various developmental and activation stages on human B cells. It is a well established negative regulator of TCR and BCR signalling. Increased expression of CD5 on either T cells or B cells protects against autoimmunity. CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. The physiological role of CD5 might be to control the generation of aberrant immune responses. In cancers, CD5 expression plays a role in the fate of tumour-specific T cells, rendering lymphocytes tolerant and unable to recognize and eliminate malignant cells. Development, selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
NCBI Accession NP_055022.2
研究領(lǐng)域 Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells

使用細(xì)節(jié)

圖像 貯存及處理 目標(biāo)詳細(xì)情況 回頁(yè)首

使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 Western blot - WB: 5-10 μg/mL Direct ELISA - This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CD5. The detection limit for Human CD5 is approximay 0.00245 ng/well.
限制 For Research Use only

貯存及處理

圖像 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁(yè)首

貯存及處理

顯示 隱藏
緩沖液 PBS with 5% trehalose
儲(chǔ)存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

xy-11929R Collagen IIⅡ型膠原α1蛋白/軟骨鈣素抗體
xy-8187R CSMD2CSMD2蛋白抗體
xy-8190R CSMD3CSMD3蛋白抗體
xy-8191R CSTP1鈣調(diào)神經(jīng)磷酸酶CSTP1抗體
xy-8192R CTAGE6CTAGE6蛋白抗體
xy-8193R CTAGE4皮膚T細(xì)胞淋巴瘤相關(guān)抗原4抗體
xy-8014R CLDND2膜蛋白CLDND2抗體
xy-6409R CHORDC1含半胱氨酸和組氨酸豐富域蛋白1抗體
xy-6432R capsid protein豬圓環(huán)病毒Ⅱ型衣殼蛋白
xy-6433R Cathelicidin抗菌肽CAMP抗體
xy-8079R CCDC134卷曲螺旋結(jié)構(gòu)域蛋白134抗體
xy-6919R CCDC69卷曲螺旋結(jié)構(gòu)域蛋白69抗體
xy-6921R CCDC98卷曲螺旋結(jié)構(gòu)域蛋白98抗體
xy-6923R CCDC70卷曲螺旋結(jié)構(gòu)域蛋白70抗體
xy-6925R CCDC51卷曲螺旋結(jié)構(gòu)域蛋白51抗體
xy-6926R CCDC125卷曲螺旋結(jié)構(gòu)域蛋白125抗體
xy-6920R CCDC50卷曲螺旋結(jié)構(gòu)域蛋白50抗體
xy-6924R CCDC90A卷曲螺旋結(jié)構(gòu)域蛋白90A抗體
xy-13810R CCDC71卷曲螺旋結(jié)構(gòu)域蛋白71抗體
xy-6927R CCDC37卷曲螺旋結(jié)構(gòu)域蛋白37抗體
xy-6922R CCDC47卷曲螺旋結(jié)構(gòu)域蛋白47抗體
xy-6928R CCDC17卷曲螺旋結(jié)構(gòu)域蛋白17抗體
xy-8080R CCDC58卷曲螺旋結(jié)構(gòu)域蛋白58抗體
xy-8081R CCDC94卷曲螺旋結(jié)構(gòu)域蛋白94抗體
xy-8085R CCDC82卷曲螺旋結(jié)構(gòu)域蛋白82抗體
xy-9076R CDK5RAP2CDK5激活結(jié)合蛋白2抗體
xy-9077R CINPCDK2相互作用蛋白抗體
xy-9078R CDK14周期蛋白依賴(lài)性激酶14抗體
xy-7999R CEACAM19癌胚抗原相關(guān)細(xì)胞粘附分子19抗體
xy-7994R CDAN1先天性紅細(xì)胞生成異常性貧血蛋白1抗體