Syntrophin-1+2+3 抗體 返回列表頁

Syntrophin-1+2+3 抗體

抗原
Syntrophin-1+2+3
適用
其他選擇 Human, Murine, Rat ((Rattus)), Chicken, Dog (Canine), Pig (Porcine), Bovine
Chicken(11),Bovine (11),Dog (Canine) (11),Human (11),Murine (11),Pig (Porcine) (11),Rat ((Rattus)) (11)
宿主
其他選擇 Rabbit
Rabbit(11)
克隆類型
多克隆
標記
其他選擇 Cy5
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Immunofluorescence (Paraffin-embedded Sections) (IF (p))(9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3),Western Blotting (WB) (3)
規(guī)格 100 μL
發(fā)貨至 中國 (更改)

Syntrophin-1+2+3 抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

顯示 隱藏
免疫原 KLH conjugated synthetic peptide derived from human Syntrophin-1+2+3
亞型 IgG
交叉反應(yīng) Murine, Rat ((Rattus)), Chicken, Dog (Canine), Pig (Porcine), Bovine
純化方法 purified by Protein A

目標詳細情況

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目標詳細情況

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背景 Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013].

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使用細節(jié)

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 652nm / 670nm

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C

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