SMAD3 抗體 返回列表頁

SMAD3 抗體 

抗原
SMAD, Mothers Against DPP Homolog 3 (SMAD3)
別名 madh3, madh3a, smad3, wu:fa99e03, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, XSmad3, XenMLP, Xmad3, madh3-A, Madh3, AU022421, Smad 3, mad3
抗原表位
其他選擇 pSer208
pSer425(56),pSer208 (39),pSer213 (35),pSer423 (32),Internal Region (27),pSer204 (24),Ser208 (21),pThr179 (14),AA 126-156 (7),Ser425 (7),AA 417-425 (6),Ser213 (6),AA 1-110 (5),AA 147-270 (4),AA 206-210 (4),AA 423-427 (4),AA 100-150 (3),AA 120-221 (3),AA 231-425 (3),C-Term (3),N-Term (3),Ser204 (3),AA 120-222 (2),AA 127-156 (2),AA 186-215 (2),Met200 (2),Pro209 (2),AA 1-111 (1),AA 1-284 (1),AA 1-425 (1),AA 122-395 (1),AA 145-194 (1),AA 170-219 (1),AA 170-396 (1),AA 179-228 (1),AA 206-220 (1),AA 31-141 (1),AA 376-425 (1),Asn175 (1),Center (1),Pro417 (1),Ser423 (1),Ser805 (1),Ser807 (1),Ser811 (1),Ser812 (1),Thr179 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(362),Murine (203),Rat ((Rattus)) (194),Bovine (65),Chicken (52),Pig (Porcine) (41),Dog (Canine) (15),Guinea Pig (12),Xenopus laevis (4),Zebrafish (2),Zebrafish (Danio rerio) (2),Frog (1),Macaque (1),Mammalian (1),Monkey (1),Others (1),Rat (Meriones) (1),Xenopus tropicalis (1)
宿主
其他選擇 Rabbit
Rabbit(337),Mouse (33)
克隆類型
多克隆
標記
其他選擇 Alexa Fluor 555
Biotin(13),FITC (12),HRP (12),Alexa Fluor 350 (7),Alexa Fluor 488 (7),Alexa Fluor 647 (7),Cy3 (7),Cy5 (7),Cy5.5 (7),Cy7 (7),Alexa Fluor 555 (6),APC (4),Alkaline Phosphatase (AP) (4),PE (4),Biotin,His tag,GST tag (1)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(251),ELISA (159),Immunohistochemistry (IHC) (133),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (87),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (69),Immunofluorescence (IF) (46),Immunocytochemistry (ICC) (32),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (22),Flow Cytometry (FACS) (11),Enzyme Immunoassay (EIA) (10),Immunoprecipitation (IP) (10),Dot Blot (DB) (9),Immunohistochemistry (Frozen Sections) (IHC (fro)) (3),Immunoassay (IA) (2),Proximity Ligation Assay (PLA) (2),Chromatin Immunoprecipitation (ChIP) (1)
規(guī)格 100 μL
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SMAD3 抗體 

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產(chǎn)品細節(jié)

顯示 隱藏
免疫原 KLH conjugated synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of pSer208 ,[NL(p-S)PN]
亞型 IgG
特異性 Excitation / Emission Wavelengths: 553nm/568nm
交叉反應(yīng) Rat ((Rattus))
純化方法 purified by Protein A

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別名 Smad3
背景 Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8), the common partner, (Smad4) that functions via its interaction to the various Smads, and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.
分子量 47kDa
基因ID 4088

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 553nm / 568nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C

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