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tau Protein抗體

抗原
tau Protein
別名 AI426939, AI551861, AW457082, CK1epsilon, CKIe, KC1epsilon, tau, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU, PHF-tau
抗原表位
其他選擇 Isoform 2, pSer214
Isoform 2(94),pSer199 (12),pSer202 (12),pSer262 (12),pSer356 (12),pSer396 (12),pSer416 (12),pSer422 (12),pSer516 (12),pSer519 (12),pSer531 (12),pSer552 (12),pSer579 (12),pSer673 (12),pSer721 (12),pSer733 (12),pSer739 (12),pThr205 (12),pThr212 (12),pThr498 (12),pThr522 (12),pThr529 (12),pSer214 (11)
適用
其他選擇 Human, Murine, Rat ((Rattus)), Dog (Canine), Bovine
Human(287),Murine (287),Rat ((Rattus)) (287),Dog (Canine) (263),Bovine (215),Chicken (96),Pig (Porcine) (12)
宿主
其他選擇 Rabbit
Rabbit(287)
克隆類型
多克隆
標(biāo)記
其他選擇 Alexa Fluor 350
Alexa Fluor 488(24),Alexa Fluor 555 (24),Alexa Fluor 647 (24),Biotin (24),Cy3 (24),Cy5 (24),Cy5.5 (24),Cy7 (24),FITC (24),HRP (24),Alexa Fluor 350 (23)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Immunofluorescence (Paraffin-embedded Sections) (IF (p))(239),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (72),Western Blotting (WB) (69)
規(guī)格 100 μL
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tau Protein抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 KLH conjugated synthetic phosphopeptide derived from human Tau protein isoform TauF around pSer214 [TP(p-S)LP]
亞型 IgG
特異性 Excitation / Emission Wavelengths: 343nm/442nm
交叉反應(yīng) Rat ((Rattus)), Dog (Canine), Bovine
純化方法 Purified by Protein A.

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目標(biāo)詳細(xì)情況

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背景 Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
分子量 49kDa
基因ID 4137

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應(yīng)用備注 WB(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500)
說明

Excitation / Emission wavelength: 343nm / 442nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100?μg/mL BSA, 50?% glycerol and 0.09?% sodium azide.
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C

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