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LMNA抗體

抗原
Lamin A/C (LMNA)
別名
2459, 74/76, CG6944, D5, DM[[O]], Dm, Dm(0), Dm0, Dm1, Dm2, DmLamin, DmO, Dm[[0]], Dm[[1]], Dm[[2]], Dm[[mit]], Dm[[o]], DmelCG6944, Dmo, LAM, Lam Dm[[0]], Lam(Dm0), LamDm[[0]], LamDm[[o]], Lam[[Dm0 ... show more
2459, 74/76, CG6944, D5, DM[[O]], Dm, Dm(0), Dm0, Dm1, Dm2, DmLamin, DmO, Dm[[0]], Dm[[1]], Dm[[2]], Dm[[mit]], Dm[[o]], DmelCG6944, Dmo, LAM, Lam Dm[[0]], Lam(Dm0), LamDm[[0]], LamDm[[o]], Lam[[Dm0]], Lamin Dm[[0]], jf27, l(2)04643, l(2)25Ec, l(2)gdh-7, l(2)gdh7, l(2)jf27, lam, lamDm0, lamDm[[0]], lamin, lamin Dm0, lamin Dm[[0]], misg, nlam, cb948, fk66d12, wu:fk66d12, fpl, idc, lfp, cddc, emd2, fpld, hgps, ldp1, lmn1, lmnc, pro1, cdcd1, cmd1a, cmt2b1, lgmd1b, Lamin-A, Dhe, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1, lmna-A, lamin-L(III)-like show less
抗原表位
其他選擇 pSer22
pSer22(14),C-Term (10),pSer392 (10),N-Term (9),AA 400-427 (7),AA 464-572 (6),Internal Region (6),AA 400-450 (5),AA 249-266 (4),AA 1-171 (3),AA 1-664 (3),AA 598-611 (3),AA 319-566 (2),AA 355-664 (2),AA 401-427 (2),AA 572-646 (2),AA 59-572 (2),Arg478Trp-Mutant (2),Asp230 (2),Isoform C (2),cleaved (2),AA 1-352 (1),AA 1-50 (1),AA 150-200 (1),AA 17-66 (1),AA 181-230 (1),AA 2-51 (1),AA 212-261 (1),AA 361-410 (1),AA 398-490 (1),AA 451-468 (1),AA 550-600 (1),AA 59-249 (1),AA 59-259 (1),Arg386 (1),Center (1),Ser17 (1),Ser22 (1),Ser778 (1),Ser78 (1),multi Epitope (1),pSer458 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus)), Dog (Canine), Pig (Porcine), Bovine
Human(195),Murine (97),Rat ((Rattus)) (90),Bovine (41),Pig (Porcine) (28),Dog (Canine) (26),Xenopus laevis (22),Fish (5),Mammalian (3),Green Monkey (Chlorocebus sabaeus) (2),Hamster (1),Rat (Meriones) (1),Sheep (Ovine) (1),Trout (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(130),Mouse (89),Chicken (3),Goat (1)
克隆類型
多克隆
標(biāo)記
其他選擇 Alexa Fluor 488
Biotin(4),FITC (4),HRP (4),Alexa Fluor 350 (3),Alexa Fluor 555 (3),Alexa Fluor 647 (3),Cy3 (3),Cy5 (3),Cy5.5 (3),Cy7 (3),Alexa Fluor 488 (2),APC (1),Alkaline Phosphatase (AP) (1),Magnetic Particles (1),PE (1),Sepharose (1)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(191),Immunofluorescence (IF) (96),Immunohistochemistry (IHC) (59),Immunocytochemistry (ICC) (57),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (51),Immunohistochemistry (Frozen Sections) (IHC (fro)) (34),ELISA (31),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (29),Immunoprecipitation (IP) (29),Flow Cytometry (FACS) (27),Immunofluorescence (Cultured Cells) (IF (cc)) (10),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (10),Immunoassay (IA) (3),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Indirect Immunofluorescence Assay (IFA) (2),Enzyme Immunoassay (EIA) (1)
規(guī)格 100 μL
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LMNA抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 KLH conjugated synthetic phosphopeptide derived from human Lamin A,pC around the phosphorylation site of pSer22
亞型 IgG
特異性 Excitation / Emission Wavelengths: 499nm/519nm
交叉反應(yīng) Rat ((Rattus)), Dog (Canine), Pig (Porcine), Bovine
純化方法 purified by Protein A

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目標(biāo)詳細(xì)情況

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別名 Lamin A/C
背景 Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A type lamins and B type lamins. The A type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A type lamins coincides with cell differentiation and as A type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A type lamins.
分子量 73kDa
基因ID 4000

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說(shuō)明

Excitation / Emission wavelength: 495nm / 519nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C

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