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TP53BP1

抗原
Tumor Protein P53 Binding Protein 1 (TP53BP1)
別名 , MGC160112, 53BP1, Tp53bp1, m53BP1, p202, Trp53bp1
適用
其他選擇 Human, Murine, Dog (Canine)
Human(139),Murine (85),Rat ((Rattus)) (49),Dog (Canine) (35),Bovine (12),Pig (Porcine) (12),Monkey (1)
宿主
其他選擇 Rabbit
Rabbit(127),Mouse (12),Goat (2),Sheep (1)
克隆類型
多克隆
標(biāo)記
其他選擇 Cy3
Biotin(6),HRP (6),Alexa Fluor 350 (3),Alexa Fluor 488 (3),Alexa Fluor 555 (3),Alexa Fluor 647 (3),Cy5 (3),Cy5.5 (3),Cy7 (3),DyLight 488 (3),DyLight 550 (3),DyLight 650 (3),FITC (3),Cy3 (2)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(91),ELISA (56),Immunohistochemistry (IHC) (42),Immunofluorescence (IF) (32),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (29),Immunocytochemistry (ICC) (28),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23),Flow Cytometry (FACS) (12),Immunoprecipitation (IP) (5),Proximity Ligation Assay (PLA) (3),Fluorescence Microscopy (FM) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
規(guī)格 100 μL
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產(chǎn)品細節(jié)

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免疫原 KLH conjugated synthetic peptide derived from human p53BP1
亞型 IgG
特異性 Excitation / Emission Wavelengths: 550nm/570nm
交叉反應(yīng) Dog (Canine)
純化方法 purified by Protein A

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別名 p53BP1
背景 P53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
分子量 220kDa
基因ID 7158

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 510.550nm / 570.615nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C

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