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PAK6抗體

抗原
P21-Activated Kinase 6 (PAK6)
別名 pak6, si:ch211-158b22.3, PAK5, 4732456M09
抗原表位
其他選擇 Center
pSer165(12),AA 151-250 (8),AA 275-305 (6),Internal Region (6),Linker Domain (6),N-Term (6),AA 131-146 (5),Middle Region (5),AA 1-681 (3),AA 116-146 (2),AA 268-297 (2),Center (2),AA 307-681 (1),AA 334-626 (1),AA 566-615 (1)
適用
其他選擇 Human
Human(96),Murine (32),Rat ((Rattus)) (30),Bovine (19),Pig (Porcine) (14),Chicken (12),Dog (Canine) (12),Horse (Equine) (2)
宿主
其他選擇 Rabbit
Rabbit(97),Mouse (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
FITC(4),Biotin (3),HRP (3),APC (2),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Alkaline Phosphatase (AP) (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),PE (2),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(68),ELISA (28),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (24),Immunohistochemistry (IHC) (21),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunoprecipitation (IP) (17),Immunofluorescence (IF) (5),Immunocytochemistry (ICC) (4),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (4),Enzyme Immunoassay (EIA) (2),Immunoassay (IA) (2),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 1 reference available
規(guī)格 0.1 mg
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發(fā)貨時(shí)間 29至35個(gè)工作日

PAK6抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 13 amino acid peptide from near the center of human PAK6
亞型 IgG
特異性 This antibody detects PAK6.
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human
純化方法 Peptide affinity chromatography

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 PAK6
背景 The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6
基因ID 56924
NCBI Accession NP_064553
UniProt Q9NQU5
研究領(lǐng)域 Signaling, Kinases/Phosphatases

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA. Western blot: 1 - 2?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

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貯存及處理

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緩沖液 PBS containing 0.02?% sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項(xiàng) Avoid repeated freezing and thawing.
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