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PDCD5抗體

抗原Programmed Cell Death 5 (PDCD5)
別名 zgc:56315, tfar19, DKFZp468P187, TFAR19, 2200003D22Rik, AA408513, Tfar19
抗原表位
其他選擇 C-Term
N-Term(14),C-Term (8),AA 5-34 (7),AA 1-125 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(46),Rat ((Rattus)) (31),Murine (30),Chicken (12),Bovine (12),Dog (Canine) (12)
宿主
其他選擇 Rabbit
Rabbit(45),Mouse (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(2),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
Western Blotting (WB)(34),ELISA (28),Immunocytochemistry (ICC) (13),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (IHC) (6),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6),Enzyme Immunoassay (EIA) (2),Immunofluorescence (IF) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 3 references available
規(guī)格 0.1 mg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 29至35個(gè)工作日

PDCD5抗體

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 PDCD5 antibody was raised against a 21 amino acid peptide from near the carboxy terminus of human PDCD5.
亞型 IgG
特異性 This antibody detects PDCD5 at C-term.
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human, mouse, rat
純化方法 Peptide affinity chromatography

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 PDCD5
背景 Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis. The nucleotide polymorphisms in the 5?-upstream region of PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.Synonyms: Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19
基因ID 9141
NCBI Accession NP_004699
UniProt O14737
研究領(lǐng)域 Cancer, Apoptosis/Necrosis

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA. Western blot: 1?μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS containing 0.02?% sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項(xiàng) Avoid repeated freezing and thawing.
儲(chǔ)存條件 4 °C/-20 °C

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