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RIMS3抗體

抗原
Regulating Synaptic Membrane Exocytosis 3 (RIMS3)
別名 RIMS3, MGC145981, Bsk, Dfl, Fgn, Gsdm1l, Gsdm3, Rco2, Rim3, si:ch211-239d6.1, NIM3, RIM3, A730060M23Rik, Nim3, mKIAA0237, Nim2
抗原表位
其他選擇 N-Term
N-Term(8),C-Term (2),AA 59-217 (1),AA 9-247 (1)
適用
其他選擇 Human, Murine
Human(29),Murine (22),Rat ((Rattus)) (15),Chicken (13),Bovine (13),Dog (Canine) (13),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(28),Mouse (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(20),ELISA (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (IHC) (9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4),Immunoassay (IA) (1)
[Pubmed] 2 references available
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

RIMS3抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

顯示 隱藏
免疫原 Rim3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Rim3.
亞型 IgG
特異性 This antibody detects Rim3 at N-term. It is predicted to have no cross-reactivity to other Rim proteins.
交叉反應(yīng) （詳細） Species reactivity (tested):Human, mouse
純化方法 Peptide affinity chromatography

目標(biāo)詳細情況

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目標(biāo)詳細情況

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別名 RIMS3
背景 Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.Synonyms: KIAA0237, Nim3, RIM 3, RIM3 gamma, Rab-3-interacting molecule 3, Regulating synaptic membrane exocytosis protein 3
基因ID 9783
NCBI Accession NP_055562
UniProt Q9UJD0
研究領(lǐng)域 Neurology

使用細節(jié)

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使用細節(jié)

顯示 隱藏
應(yīng)用備注 ELISA. Western blot: 0.5 - 1?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

顯示 隱藏
緩沖液 PBS containing 0.02?% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
儲存條件 4 °C/-20 °C

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