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APOE抗體

抗原
Apolipoprotein E (APOE)
別名 ad2, apoprotein, im:7036787, wu:fb69a05, zgc:110064, apoe, AI255918, AD2, LDLCQ5, LPG, APOEA, Apo-E
抗原表位
其他選擇 C-Term, AA 263-292
C-Term(18),N-Term (6),Internal Region (5),Isoform E3 (4),AA 19-317 (2),AA 1-129 (1),AA 14-167 (1),AA 140-160 (1),AA 19-181 (1),AA 255-317 (1),AA 263-292 (1),AA 37-86 (1),Met86 (1)
適用
其他選擇 Human
Human(191),Murine (50),Rat ((Rattus)) (33),Rabbit (5),Hamster (4),Mammalian (1),Monkey (1)
宿主
其他選擇 Rabbit
Rabbit(112),Goat (67),Mouse (52)
克隆類型 (克隆位點(diǎn))
多克隆 (RB15180)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(15),HRP (10),FITC (4),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB)(164),ELISA (119),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (50),Immunohistochemistry (IHC) (41),Enzyme Immunoassay (EIA) (20),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunohistochemistry (Frozen Sections) (IHC (fro)) (19),Immunoprecipitation (IP) (15),Immunodiffusion (ID) (11),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (11),Flow Cytometry (FACS) (10),Radioimmunoassay (RIA) (8),Immunocytochemistry (ICC) (7),Immunoelectrophoresis (IEP) (7),Immunofluorescence (IF) (3),Radial Immunodiffusion (RID) (3),Dot Blot (DB) (2),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Toxin Binding Inhibition Assay (TOBI) (2),Fluorescence Microscopy (FM) (1),Functional Studies (Func) (1),Immunoassay (IA) (1),Labeling (Lbl) (1),Ouchterlony Double Diffusion (ODD) (1),Thin Layer Immunoassay (TIA) (1)
規(guī)格 400 μL
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發(fā)貨時(shí)間 9至13個(gè)工作日

APOE抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 AA from the C-terminal region of human APOE.
克隆位點(diǎn) RB15180
亞型 Ig
特異性 This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270~300 amino acids from the C-terminal region of human APOE.
預(yù)測反應(yīng) Monkey,Rabbit
純化方法 This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 APOE
背景 Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Synonyms: Apolipoprotein E [Precursor], Apo-E, APOE
分子量 36154 DA
基因ID 348
UniProt P02649
研究領(lǐng)域 Metabolism, Cell Structure

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 WB = 1:1000, IHC = 1:10-50
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 2 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C

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