突觸結(jié)合蛋白11抗體 返回列表頁

突觸結(jié)合蛋白11抗體

英文名稱 Synaptotagmin XI
中文名稱 突觸結(jié)合蛋白11抗體
別    名 Synaptotagmin 11; Synaptotagmin 12; Synaptotagmin XI; Synaptotagmin-11; synaptotagmin XII; synaptotagmin-XII; Synaptotagmin11; Synaptotagmin12; Synaptotagmin-11; Synaptotagmin-12; SynaptotagminXI; SYT 11; SYT 12; SYT-11; SYT-12; Syt XI; Syt11; SYT11_HUMAN; SYT12; SytXI; DKFZp781D015; KIAA0080; MGC10881; MGC17226.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synaptotagmin XI (51-100aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson’s disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson’s disease.

Function:
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.xy-2035R    LIS1無腦回的致病基因LIS1抗體
xy-2556R    LAMP3溶酶體相關(guān)膜蛋白3抗體
xy-1758R    L-ENK亮氨酸腦啡肽抗體
xy-2912R    LC3B/MAP LC3β/MAP1A自噬微管相關(guān)蛋白輕鏈3抗體
xy-11780R    LMX1b指甲髕骨綜合征相關(guān)蛋白NPS1抗體
xy-4843R    LC3B自噬微管相關(guān)蛋白輕鏈β3抗體
xy-8361R    LRRC59LRRC59蛋白抗體
xy-8362R    LRRC41LRRC41蛋白抗體
xy-6431R    LHR促黃體生成素受體抗體
xy-11131R    alpha Lactalbumin乳清蛋白α抗體
xy-11132R    Lamin B2核纖層蛋白B2抗體
xy-1086R    Laminin alpha 5層粘蛋白α5抗體
xy-0619R    L-CitrullineL-瓜氨酸抗體
xy-9487R    LACE1泌乳升高蛋白1抗體
xy-9562R    LAPTM4A溶酶體相關(guān)膜蛋白4α抗體
xy-9563R    DIF14分化相關(guān)基因14抗體
xy-9561R    LACTB2β內(nèi)酰胺酶樣蛋白2抗體
xy-11088R    LRFN3神經(jīng)突觸粘附樣分子4抗體
xy-5729R    LGALS3BP可溶性半乳糖凝集素3結(jié)合蛋白抗體
xy-4604R    Leptin瘦素抗體
xy-7533R    Lipin 1磷脂酸磷酸酯酶LPIN1抗體
xy-8609R    LGR6G蛋白偶聯(lián)受體6抗體
xy-3801R    Lambda Light Chainλ輕鏈抗體
xy-2379R    LAMP2溶酶體相關(guān)膜蛋白2抗體
xy-9672R    LAS2肺腺瘤易感蛋白2抗體
xy-5410R    phospho-LEO1(Ser551)磷酸化RNA聚合酶相關(guān)蛋白LEO1抗體
xy-4081R    LATS2腫瘤抑制基因LATS2抗體
xy-5155R    phospho-LSP1 (Ser204)磷酸化白細(xì)胞F肌動蛋白結(jié)合蛋白抗體
xy-4082R    phospho-LATS2 (Ser83)磷酸化腫瘤抑制基因LATS2抗體
xy-5156R    phospho-LSP1 (Ser252)磷酸化白細(xì)胞F肌動蛋白結(jié)合蛋白抗體
xy-5154R    LSP1白細(xì)胞F肌動蛋白結(jié)合蛋白抗體
xy-5138R    LZTFL1亮氨酸拉鏈轉(zhuǎn)錄因子樣1抗體
xy-5122R    Laminin B2 gamma 1層粘連蛋白B2γ1抗體