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磷酸化血清應(yīng)答因子抗體

英文名稱 Phospho-SRF (Ser77)
中文名稱 磷酸化血清應(yīng)答因子抗體
別    名 Serum Response Factor SRF (phospho S77); SRF (phospho Ser77); P-SRF (Ser77); c fos serum response element binding factor; Serum Response Factor SRF; c fos serum response element binding transcription factor; ELK3; ERP; MCM 1; MCM-1; MCM1; OTTHUMP00000039820; SAP2; Serum response factor; SRF; SRF serum response factor c fos serum response element binding transcription factor; SRF_HUMAN.

說(shuō) 明 書(shū) 0.1ml  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  干細(xì)胞  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human SRF around the phosphorylation site of Ser77
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].

Function:
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.xy-7932R    PPP2R1B蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基1B抗體
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xy-7929R    PPM1B蛋白質(zhì)磷酸酶1B抗體（PP2Cβ）
xy-7930R    PPM1G蛋白質(zhì)磷酸酶1G抗體（PP2Cγ）
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xy-11992R    PPP2R5D蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基5D/PP2A-B56-δ抗體
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xy-11218R    Pumilio 1PUM1蛋白抗體
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xy-11215R    Plexin B2神經(jīng)叢蛋白B2抗體
xy-11222R    Phospho-p53BP1 (Ser1778)磷酸化p53結(jié)合蛋白1抗體
xy-11253R    PISTPDZ結(jié)構(gòu)域蛋白GOPC抗體
xy-11204R    PAX6轉(zhuǎn)錄因子Pax6抗體
xy-11206R    PLAGL1多型性腺瘤基因樣蛋白1抗體
xy-8687R    p53 (FL-393)腫瘤抑制基因p53抗體
xy-9511R    PAR4蛋白酶激活受體4抗體
xy-11139R    PCDHB5原鈣粘蛋白β5抗體
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xy-6768R    PEF1調(diào)亡誘導(dǎo)因子家族蛋白PEF1抗體
xy-6765R    Perilipin A+B脂滴包被蛋白A+B抗體
xy-6767R    PDC6I調(diào)亡誘導(dǎo)因子6相互作用蛋白/多巴胺受體相互作用蛋白4抗體
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xy-12108R    P2RX5三磷酸腺苷受體P2X5抗體
xy-12109R    P2X5b三磷酸腺苷受體P2X5b抗體
xy-12110R    P2RX6三磷酸腺苷受體P2X6抗體
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