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分泌性磷蛋白24抗體

英文名稱 SPP24
中文名稱 分泌性磷蛋白24抗體
別    名 Secreted phosphoprotein 24; Spp-24; Secreted phosphoprotein 2; SPP2; SPP-2; SPP 2; SPP24_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16/21kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPP24/SPP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

PubMed PubMed
產(chǎn)品介紹 background:
SPP24, also known as secreted phosphoprotein 2, is a 211 amino acid secreted protein that belongs to the cystatin superfamily. Expressed in liver and plasma, SPP24 may play a role in coordinating an aspect of bone turnover. The gene that encodes SPP24 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximay 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial omeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Subcellular Location:
Secreted.

Tissue Specificity:
Detected in liver and plasma.

Similarity:
Belongs to the SPP2 family.xy-2671R    TBX3轉(zhuǎn)錄因子Tbx3抗體
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xy-6065R    TCF3轉(zhuǎn)錄因子3抗體（螺旋環(huán)螺旋蛋白HE47）
xy-6066R    phospho-TCF3(Thr355)磷酸化轉(zhuǎn)錄因子3抗體
xy-4662R    phospho-TCF3 (Ser39)磷酸化轉(zhuǎn)錄因子3抗體
xy-3599R    Tbx21T細(xì)胞介導(dǎo)的轉(zhuǎn)錄調(diào)節(jié)因子Tbx21抗體
xy-3456R    Phospho-TrkA(Tyr496) +TrkB(Tyr516)磷酸化酪氨酸激酶A抗體
xy-3732R    Phospho-TrkA (Tyr785)+TrkB (Tyr816)磷酸化酪氨酸激酶A抗體
xy-3459R    Phospho-Tuberin (Ser1254)磷酸化馬鈴薯球蛋白(結(jié)節(jié)性硬化)抗體
xy-3437R    Phospho-Tyk2(Tyr1054 + Tyr1055)磷酸化非受體酪氨酸蛋白激酶2抗體
xy-3458R    Phospho-Troponin I(Ser23 + Ser24)磷酸化鈣調(diào)節(jié)蛋白-1抗體
xy-3415R    Phospho-TORC2 (Ser171)磷酸化CREB轉(zhuǎn)錄共激活因子TORC2抗體
xy-1511R    TRP2酪氨酸酶相關(guān)蛋白2抗體
xy-2441R    TWIST proteinTWIST蛋白抗體
xy-3462R    Phospho-Tyrosine Hydroxylase (Ser40)磷酸化酪氨酸羥化酶抗體
xy-10542R    Topoisomerase I拓普西異構(gòu)酶Ⅰ抗體
xy-13712R    TIN-Ag腎小管間質(zhì)腎炎抗原抗體
xy-13622R    TMEM176A跨膜蛋白176A抗體
xy-13623R    TMEM176A跨膜蛋白176A抗體
xy-10266R    TBX3轉(zhuǎn)錄因子Tbx3抗體
xy-10505R    tinagl1tinagl1抗體
xy-8534R    TRPV5辣椒素受體5抗體
xy-0149R    TRA1 variant腫瘤排斥抗原gp96 1 變異體抗體
xy-2535R    TFPI/LACI組織因子途徑抑制劑抗體
xy-6744R    TRIM47星形細(xì)胞瘤高表達(dá)蛋白抗體（環(huán)指蛋白100）
xy-12863R    TUBB5微管蛋白β5抗體
xy-3580R    TRIM24轉(zhuǎn)錄中介因子Tif1α抗體
xy-3581R    KAP1轉(zhuǎn)錄中介因子Tif1β抗體
xy-3423R    Phospho-TIF1 beta(Ser824)磷酸化轉(zhuǎn)錄中介因子Tif1β抗體
xy-3592R    Tyk2非受體酪氨酸蛋白激酶2抗體
xy-3582R    TIF1 gamma轉(zhuǎn)錄中介因子Tif1γ抗體
xy-3583R    TLK1調(diào)節(jié)染色體組裝激酶1抗體