細胞分化蛋白SEPT6抗體 返回列表頁

細胞分化蛋白SEPT6抗體

英文名稱 SEPT6
中文名稱 細胞分化蛋白SEPT6抗體
別    名 Nkrf; RCG53214, isoform CRA_d; SEP2; SEPT2; SEPT 2; SEPT-2; SEPT6; SEPT-6; SEPT6/MLL FUSION GENE; SEPT6_HUMAN; Septin 2; Septin2; Septin-2; Septin 6; Septin6; Septin-6.
 
說 明 書 0.2ml  
研究領域 細胞生物  細胞周期蛋白  細菌及病毒  細胞分化  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEPT6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008].

Function:
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication.

Subunit:
Septins polymerize into heterooligomeric protein complexes that form filaments, and associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation. Filaments are assembled from asymmetrical heterotrimers, composed of SEPT2, SEPT6 and SEPT7 that associate head-to-head to form a hexameric unit. Within the trimer, directly interacts with SEPT2 and SEPT7. Also interacts with SEPT9 and SEPT12. Interaction with SEPT12 alters filament structure. Interacts with SOCS7. Interacts with HCV NS5B and with HNRNPA1.xy-13690R    MS4A14睪丸發(fā)育相關蛋白抗體
xy-13691R    MS4A15MS4A15蛋白抗體
xy-13692R    MS4A6A四度跨膜蛋白3抗體
xy-6818R    MAGEA12黑色素瘤相關抗原12抗體
xy-6819R    MAGEA2黑色素瘤相關抗原2抗體
xy-6820R    MAGEA5黑色素瘤相關抗原5抗體
xy-10158R    Msx2同源盒基因Msx2抗體
xy-5470R    Phospho-MDM2(Thr218)磷酸化雙微體2癌基因抗體
xy-5471R    Phospho-MDM2(Ser186)磷酸化雙微體2癌基因抗體
xym-2182M    Melamine(1B12)三聚氰胺單克隆抗體
xy-6821R    MAGEB1黑色素瘤相關抗原B1抗體
xy-2721R    MCM5微小染色體維持缺陷蛋白5抗體
xy-4293R    MACC1結腸癌轉移相關蛋白1抗體
xy-4597R    MMP-1基質金屬蛋白酶-1抗體
xy-5483R    phospho-MEF2C(Thr300)磷酸化肌細胞增強因子2C抗體
xy-5485R    Phospho-MEF2A(Thr319)磷酸化肌細胞增強因子2抗體
xy-5474R    phospho-MBP(Thr232)磷酸化髓鞘堿性蛋白抗體
xy-5475R    phospho-MBP(Tyr203)磷酸化髓鞘堿性蛋白抗體
xy-5478R    phospho-MYL6(Tyr29+Ser30)磷酸化肌球蛋白輕鏈6抗體
xy-5476R    phospho-P38 MAPK (Thr180)磷酸化p38MAPK抗體
xy-5477R    phospho-p38 MAPK (Tyr323)磷酸化p38MAPK抗體
xy-5480R    phospho-MEF2C(Ser396)磷酸化肌細胞增強因子2C抗體
xy-5487R    phospho-MAPK8 ( Thr183 + Tyr185)磷酸化氨基末端激酶2抗體
xy-12201R    MELK蛋白激酶MPK38抗體
xy-12206R    MGST1微粒體谷胱甘肽S轉移酶1抗體
xy-10074R    MUC13粘蛋白13抗體
xy-8689R    MEPE細胞外基質磷酸化抗體
xy-2725R    Mast Cell Tryptase肥大細胞蛋白酶7抗體
xy-4128R    MAP4微管相關蛋白4抗體
xy-5120R    MSS126S蛋白酶調節(jié)亞型7抗體
xy-3629R    MEG1蛋白酪氨酸磷酸酶非受體型4抗體
xy-13355R    MBOAT4腦腸肽O?；D移酶抗體
xy-5272R    MRG15轉錄調控因子MRG15抗體