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細(xì)胞質(zhì)和紡錘體機(jī)化蛋白A抗體

英文名稱 SPECC1L
中文名稱 細(xì)胞質(zhì)和紡錘體機(jī)化蛋白A抗體
別    名 Cytokinesis and spindle organization A; Cytospin-A; CYTSA; CYTSA_HUMAN; Renal carcinoma antigen NY-REN-22; SPECC1-like protein; specc1l; Sperm antigen with calponin homology and coiled-coil domains 1-like.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 125kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPECC1L
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]

Function:
Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration. 

Subunit:
May interact with both microtubules and actin cytoskeleton. 

Subcellular Location:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell junction, gap junction. Note=Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center. xy-3909R    Megalin糖蛋白gp330抗體
xy-5499R    phospho-MyoD1(Ser200)磷酸化肌原調(diào)節(jié)蛋白抗體
xy-4134R    MAP4K1造血祖細(xì)胞激酶1抗體
xy-4133R    MAP4K4絲裂原活化蛋白激酶MAP4K4抗體
xy-5495R    phospho-MAP3K7IP1(Ser423)磷酸化轉(zhuǎn)化生長因子β活化激酶結(jié)合蛋白1抗體
xy-5496R    phospho-MAP3K7IP1(Thr431)磷酸化轉(zhuǎn)化生長因子β活化激酶結(jié)合蛋白1抗體
xy-5497R    phospho-MAPK3(Tyr204)磷酸化絲裂原活化蛋白激酶3抗體
xy-5498R    phospho-MEK2(Ser226)磷酸化絲裂原活化蛋白激酶激酶2抗體
xy-5501R    phospho-MEF2D(Ser180)磷酸化肌細(xì)胞特異性增強(qiáng)因子2D抗體
xy-5502R    phospho-MEF2D(Ser444)磷酸化肌細(xì)胞特異性增強(qiáng)因子2D抗體
xy-5503R    Phospho-MAPKAPK2(Ser272)磷酸化絲裂原活化蛋白激酶活化的蛋白激酶2抗體
xy-5504R    phospho-MAPKAPK5(Thr182)磷酸化p38調(diào)節(jié)/激活蛋白激酶抗體
xy-5505R    phospho-MAPKAPK5(Ser93)磷酸化p38調(diào)節(jié)/激活蛋白激酶抗體
xy-5494R    phospho-MAP4K1(Ser171)磷酸化造血祖細(xì)胞激酶抗體
xy-4137R    PRAKp38調(diào)節(jié)/激活蛋白激酶抗體
xy-4136R    MEF2D肌細(xì)胞特異性增強(qiáng)因子2D抗體
xy-5493R    phospho-MAP4K4(Ser801)磷酸化絲裂原活化蛋白激酶MAP4K4抗體
xy-5500R    Phospho-MARCKS(Ser170)磷酸化丙氨酸蛋白激酶C底物Marcks抗體
xy-8304R    MTGR1髓易位基因相關(guān)蛋白1抗體
xy-7754R    BBS6巴德-畢德氏綜合征蛋白BBS6抗體
xy-7750R    MKLP2有絲分裂驅(qū)動蛋白樣2抗體
xy-7810R    MFAP1微原纖維膠原相關(guān)蛋白1抗體
xy-7799R    MND1減數(shù)分裂核分裂蛋白1抗體
xy-6386R    MDFIC肌原調(diào)節(jié)抑制蛋白抗體
xy-6388R    MDM2BP雙微體2癌基因結(jié)合蛋白抗體
xy-5788R    MMP20基質(zhì)金屬蛋白酶20
xy-5762R    MRP8多藥耐藥相關(guān)蛋白8抗體
xy-5761R    MRP7多藥耐藥相關(guān)蛋白7抗體
xy-5753R    phospho-MLF1 Interacting Protein(Thr78)磷酸化卡波西氏肉瘤皰疹病毒潛伏核抗原相互作用蛋白1抗體
xy-5751R    MATK酪氨酸蛋白激酶細(xì)胞分裂素抗體
xy-5752R    MLF1 Interacting Protein卡波西氏肉瘤皰疹病毒潛伏核抗原相互作用蛋白1抗體
xy-6231R    MAGEF1黑色素瘤抗原F蛋白家族1抗體
xy-5841R    MGAT5糖蛋白GNTVA抗體
xy-5842R    MIIPIGFBP2結(jié)合蛋白/遷移和侵潤抑制蛋白抗體
xy-11028R    MAP1B微管相關(guān)蛋白1B抗體
xy-4919R    MSH3錯配修復(fù)蛋白3抗體
xy-11092R    MDGA2神經(jīng)元膜糖蛋白錨定蛋白2抗體
xy-11038R    MYRIPMYRIP蛋白抗體
xy-11093R    Myelin PLP髓磷酯髓鞘蛋白1抗體
xy-4910R    MCSF巨噬細(xì)胞克隆刺激因子抗體
xy-9338R    MARCH4膜相關(guān)環(huán)指蛋白4抗體
xy-4705R    MLCK肌球蛋白輕鏈激酶抗體
xy-7850R    MPS1單極紡錘體蛋白激酶1抗體
xy-7840R    Mad2L2有絲分裂阻滯缺陷2樣蛋白2抗體
xy-11297R    Monoamine Oxidase B單胺氧化酶B抗體
xy-11298R    MCM4微小染色體維持缺陷蛋白4抗體