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鈉通道蛋白8α抗體

英文名稱 SCN8A/Nav1.6
中文名稱 鈉通道蛋白8α抗體
別    名 CerIII; hNa6/Scn8a voltage gated sodium channel; MED; Motor endplate disease; NaCh 6; NaCh6; Nav 1.6; Nbna1; PN 4; PN4; Scn8a; SCN8A_HUMAN; Sodium channel protein type 8 alpha subunit; Sodium channel protein type 8 subunit alpha; Sodium channel protein type VIII alpha subunit; Sodium channel protein type VIII subunit alpha; Sodium channel voltage gated type VIII alpha; Sodium channel voltage gated type VIII alpha polypeptide; Sodium channel voltage gated type VIII alpha subunit; Voltage gated sodium channel subunit alpha Nav1.6; Voltage-gated sodium channel subunit alpha Nav1.6.
   
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  神經生物學  信號轉導  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 220kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCN8A/Nav1.6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.

Function:
Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.

Subcellular Location:
Cytoplasm. Cytoplasm, perinuclear region.xy-6216R    ROR beta維甲酸相關孤兒受體β抗體
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xy-3832R    RHEBRas蛋白腦組織同源類似物RHEB蛋白抗體
xy-2330R    RAP2B原癌基因相關蛋白RAP2B抗體
xy-6016R    RBBP5視網膜母細胞瘤結合蛋白5抗體
xy-10173R    ROCK2Rho相關蛋白激酶2抗體
xy-7133R    RRM2核糖核苷酸還原酶亞基R2抗體
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xy-3675R    R-cadherinR-鈣粘附分子抗體
xy-6168R    RAB8Bras癌基因家族RAB8B抗體
xy-6169R    RALBRas樣蛋白B抗體
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xy-7709R    Retinoic acid induced 17維甲酸誘導蛋白17抗體
xy-6902R    RanGAP1RAN GTPase酶激活蛋白1抗體
xy-7723R    REC8減數分裂重組蛋白家族REC8抗體
xy-3676R    RALDH2視黃醛脫氫酶2型抗體
xy-3691R    REG4再生基因蛋白4抗體
xy-11619R    RTP3受體轉運蛋白3抗體
xy-11620R    RGS21G蛋白信號調節(jié)蛋白21抗體
xy-10036R    REG4再生基因蛋白4抗體
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