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磷酸化原癌基因蛋白18

英文名稱 Phospho-Stathmin 1 (Ser25)
中文名稱 磷酸化原癌基因蛋白18
別    名 Stathmin 1 (phospho S25); Stathmin 1 (Phospho-Ser25); Stathmin (Phospho Ser25); Stathmin (Phospho S25); Lag; LAP 18; LAP18; Leukemia associated phosphoprotein p18; Metablastin; Oncoprotein 18; OP 18; OP18; p18; p19; Phosphoprotein 19; Phosphoprotein p19; PP17; PP19; PR22; Pr22 protein; Prosolin; Protein Pr22; SMN; Stathmin; Stathmin1; STMN 1; STMN1; STMN1_HUMAN.
   
說 明 書 0.1ml  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Stathmin around the phosphorylation site of Ser25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Function:
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear.

Subunit:
Binds to two alpha/beta-tubulin heterodimers. Interacts with KIST.

Subcellular Location:
Cytoplasm, cytoskeleton.xy-1415R    YY1核轉(zhuǎn)錄調(diào)節(jié)因子YY1抗體
xy-3475R    Phospho-YAP1(Ser127)磷酸化原癌基因Yes相關(guān)蛋白1抗體
xy-4166R    YES1原癌基因酪氨酸蛋白激酶Yes1抗體
xy-5591R    phospho-YES1 (Tyr426)磷酸化原癌基因酪氨酸蛋白激酶Yes1抗體
xy-5592R    phospho-YES1(Tyr537)磷酸化原癌基因酪氨酸蛋白激酶Yes1抗體
xy-3478R    Phospho-ZAP70 (Tyr315 + Tyr319)磷酸化zeta相關(guān)蛋白70抗體
xy-3479R    Phospho-ZAP70 (Tyr493)磷酸化zeta相關(guān)蛋白70抗體
xy-3620R    Phospho-Zyxin (Ser142+Ser143)磷酸化斑聯(lián)蛋白抗體
xy-13576R    ZBTB41鋅指蛋白924抗體
xy-11608R    ZIC3內(nèi)臟異位相關(guān)蛋白/鋅指蛋白203抗體
xy-13564R    zbtb11鋅指蛋白913抗體
xy-13557R    ZBT24鋅指蛋白450抗體
xy-13560R    ZA20D3鋅指蛋白20D3抗體
xy-13553R    ZBED3鋅指蛋白BED3抗體
xy-13572R    ZBTB38鋅指蛋白ZBTB38抗體
xy-13562R    ZADH2鋅結(jié)合乙醇脫氫酶結(jié)構(gòu)域蛋白2抗體
xy-13567R    ZBTB3鋅指蛋白ZBTB3抗體
xy-13551R    ZBBX鋅指蛋白ZBBX抗體
xy-12253R    ZFP219鋅指蛋白219抗體
xy-12254R    ZFP36L1EGF應(yīng)答因子1抗體抗體
xy-12255R    phospho-ZFP36L1(Ser334)磷酸化鋅指蛋白36抗體
xy-12240R    ZNF347鋅指蛋白347抗體
xy-13555R    ZBED5鋅指蛋白BED5抗體
xy-12241R    ZNF704鋅指蛋白704抗體
xy-13586R    ZNF434宮頸癌抑癌蛋白5/鋅指蛋白434抗體
xy-0354R    ZCWCC1ZCWCC1抗體
xy-0628R    ZNF300鋅指蛋白300抗體
xy-13573R    ZBTB39鋅指蛋白ZBTB39抗體
xy-11609R    Zic1鋅指蛋白201抗體
xy-11610R    Zic2鋅指蛋白Zic2抗體