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核突觸蛋白-α抗體(N端)
英文名稱 alpha-Synuclein
中文名稱 核突觸蛋白-α抗體(N端)
別 名 Alpha synuclein; Alpha-Synuclein; Alpha-synuclein, isoform NACP140; alpha SYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid precursor; Non-A-beta component of alzheimers disease amyloid , precursor of; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease (autosomal dominant, Lewy body) 4; Parkinson disease familial 1; PD 1; PD1; Syn; SNCA; Snca synuclein, alpha (non A4 component of amyloid precursor); SYUA_HUMAN; Synuclein alpha; Synuclein, alpha (non A4 component of amyloid precursor);
說 明 書 0.1ml 0.2ml
研究領域 細胞生物 神經生物學 細胞凋亡
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Pig, Cow,
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
細胞定位 細胞核 細胞漿 細胞膜
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human alpha-Synuclein N-terminus
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產品介紹 background:
Alpha Synuclein is implicated in the regulation of dopamine release and transport. It is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). In the nervous system, alpha Synuclein is primarily located at presynaptic terminals and is found membrane bound in dopaminergic neurons. It can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies), including Parkinson's Disease. Alpha Synuclein induces fibrillization of microtubule associated protein tau and reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase 3 activation. Alpha synuclein is a protein phosphorylated predominantly on serine residues.xy-7006R RASD2腫瘤血管內皮標記蛋白2抗體
xy-9159R RNF14環(huán)指蛋白14抗體
xy-5816R RRAGARAS相關GTP結合蛋白A抗體
xy-5805R RIPK-1絲氨酸蘇氨酸激酶1受體相互作用蛋白抗體
xy-5815R RAIDDCASP2凋亡相關蛋白抗體
xy-5940R RAD54BDNA修復和重組蛋白RAD54B抗體
xy-5941R RRAS2畸胎瘤癌基因RAS相關病毒抗體
xy-5954R RASA3Ras-GTP酶激活蛋白3抗體
xy-11798R Reticulon 1神經內分泌特異性蛋白抗體
xy-6214R RDH11視黃醇脫氫酶11/丙型肝炎病毒核心蛋白抗體
xy-6216R ROR beta維甲酸相關孤兒受體β抗體
xy-6155R RAP1GDS1G蛋白GTP-GDP解離刺激因子1抗體
xy-6180R Rab3A+Rab3B+Rab3C+Rab3Dras癌基因家族Rab3A--Rab3D抗體
xy-6156R RASGEF1A鳥嘌呤核苷酸交換因子rasgef1a抗體
xy-6514R RLLM1胰腺癌轉移相關蛋白RLLM1抗體
xy-6511R RNF45環(huán)指蛋白45/自分泌運動因子受體抗體
xy-6215R ROR alpha維甲酸相關孤兒受體α抗體
xy-6217R RORG維甲酸相關孤兒受體γ抗體
xy-6157R RAB4癌基因RAS相關蛋白Rab4A抗體
xy-2960R ROM-KATP調節(jié)鉀離子通道ROM K抗體
xy-3868R Rab24ras基因相關蛋白Rab24抗體
xy-11941R RDH10視黃醇脫氫酶10抗體
xy-3832R RHEBRas蛋白腦組織同源類似物RHEB蛋白抗體
xy-2330R RAP2B原癌基因相關蛋白RAP2B抗體
xy-6016R RBBP5視網膜母細胞瘤結合蛋白5抗體
xy-10173R ROCK2Rho相關蛋白激酶2抗體
xy-7133R RRM2核糖核苷酸還原酶亞基R2抗體
xy-4860R Runx3Runx3抗體
xy-10097R RRAGCRAS相關GTP結合蛋白C抗體
xy-3675R R-cadherinR-鈣粘附分子抗體
xy-6168R RAB8Bras癌基因家族RAB8B抗體
xy-6169R RALBRas樣蛋白B抗體
xy-6123R Rb2 p130視網膜母細胞瘤相關蛋白p130抗體
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