胚胎干細(xì)胞關(guān)鍵蛋白抗體 返回列表頁

胚胎干細(xì)胞關(guān)鍵蛋白抗體

英文名稱 SOX2
中文名稱 胚胎干細(xì)胞關(guān)鍵蛋白抗體
別    名 transcriptional factor SOX2; ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MGC148683; MGC2413; RGD1565646; Sex determining region Y box 2; Sex determining region Y-box 2; SOX 2; SRY (sex determining region Y) box 2; SRY box containing gene 2; SRY related HMG box 2; SRY related HMG box gene 2; SRY-box 2; ysb; SOX2_HUMAN; Transcription factor SOX-2; SOX2_HUMAN.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  干細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Transcription factor SOX-2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008].

Function:
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.xy-2737R    TREML2髓系細(xì)胞觸發(fā)受體樣轉(zhuǎn)錄因子2抗體
xy-10406R    Thyroid peroxidase甲狀腺過氧化物酶抗體
xy-10407R    Thrombopoietin血小板生成素/巨核細(xì)胞集落刺激因子抗體
xy-10404R    TRPC1瞬時受體電位通道1抗體
xy-15510R    TRP1酪氨酸酶相關(guān)蛋白1抗體
xy-13669R    TIFA推定NFκB激活蛋白20抗體
xy-13670R    TOM1L1Src激活和信號分子蛋白抗體
xy-13671R    TRAF6BP腫瘤壞死因子受體相關(guān)蛋白6結(jié)合蛋白抗體
xy-12403R    TLE4B淋巴細(xì)胞基因1抗體
xy-1496R    LATT細(xì)胞活化連接蛋白抗體
xy-12367R    TAZ轉(zhuǎn)錄共激活因子TAZ抗體
xy-2134R    Thrombin light chain凝血酶(凝血因子II)輕鏈抗體
xy-10387R    Thrombin Activation peptide fragment 1凝血酶(凝血因子II)激活肽1抗體
xy-10388R    Thrombin Activation peptide fragment 2凝血酶(凝血因子II)激活肽2抗體
xy-15504R    TafazzinTafazzin蛋白抗體
xy-15505R    TECTEC酪氨酸激酶蛋白抗體
xy-15506R    TRPV6鈣轉(zhuǎn)運(yùn)蛋白1抗體
xy-10395R    TIMP-2金屬蛋白酶組織抑制因子-2抗體
xy-3852R    TNFRSF19腫瘤壞死因子配體超家族成員19抗體
xy-3851R    TNFSF9腫瘤壞死因子配體超家族成員9抗體
xy-4041R    Transaldolase 1轉(zhuǎn)醛醇酶抗體
xy-5142R    TAF12TATA框結(jié)合蛋白關(guān)聯(lián)因子12抗體
xy-5136R    Elongin B轉(zhuǎn)錄延伸因子B2抗體
xy-0291R    TG兔抗甲狀腺球蛋白
xy-2803R    TNFAIP3腫瘤壞死因子α誘導(dǎo)蛋白3抗體
xy-2888R    TRPM2瞬時受體電位離子通道蛋白/M亞家族抗體
xy-6884R    TSSC3腫瘤抑制轉(zhuǎn)移候選基因3抗體
xy-6885R    TTI1轉(zhuǎn)錄因子相互作用蛋白1抗體
xy-5092R    TNFSF15腫瘤壞死因子配體超家族成員15抗體
xy-3846R    TGF beta 5轉(zhuǎn)移生長因子β5抗體
xy-5418R    phospho-Tau protein(Ser235)磷酸化微管相關(guān)蛋白抗體
xy-5419R    phospho-Tau protein(Thr212)磷酸化微管相關(guān)蛋白抗體
xy-5420R    phospho-Tau protein(Thr205)磷酸化微管相關(guān)蛋白抗體
xy-5421R    phospho-Tau protein(Ser356)磷酸化微管相關(guān)蛋白抗體
xy-8453R    phospho-Tau protein(Thr181)磷酸化微管相關(guān)蛋白抗體