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鋅指蛋白43抗體

英文名稱 ZNF43
中文名稱 鋅指蛋白43抗體
別    名 ARK1; AURKA; AURORA2; BTAK; HTF6; KOX27; STK15; Zinc finger protein 39; Zinc finger protein 43; Zinc finger protein HTF6; Zinc finger protein KOX27; Zinc protein HTF6; ZNF39; ZNF39L1; ZNF43; ZNF43_HUMAN.
 
說 明 書 0.2ml  
研究領域 轉錄調節(jié)因子  t-淋巴細胞  b-淋巴細胞  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 94kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF43
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008]

Function:
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1, PARD3, PPP1R2, PLK1, RASSF1, TACC3, p53/TP53 and TPX2. Regulates KIF2A tubulin depolymerase activity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. Also acts as a key regulatory component of the p53/TP53 pathway, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.xy-3477R    Phospho-YB1(Ser102)磷酸化DNA結合蛋白B抗體
xy-3476R    Phospho-YAP1(Tyr407)磷酸化原癌基因Yes相關蛋白1抗體
xy-1415R    YY1核轉錄調節(jié)因子YY1抗體
xy-3475R    Phospho-YAP1(Ser127)磷酸化原癌基因Yes相關蛋白1抗體
xy-4166R    YES1原癌基因酪氨酸蛋白激酶Yes1抗體
xy-5591R    phospho-YES1 (Tyr426)磷酸化原癌基因酪氨酸蛋白激酶Yes1抗體
xy-5592R    phospho-YES1(Tyr537)磷酸化原癌基因酪氨酸蛋白激酶Yes1抗體
xy-3478R    Phospho-ZAP70 (Tyr315 + Tyr319)磷酸化zeta相關蛋白70抗體
xy-3479R    Phospho-ZAP70 (Tyr493)磷酸化zeta相關蛋白70抗體
xy-3620R    Phospho-Zyxin (Ser142+Ser143)磷酸化斑聯蛋白抗體
xy-13576R    ZBTB41鋅指蛋白924抗體
xy-11608R    ZIC3內臟異位相關蛋白/鋅指蛋白203抗體
xy-13564R    zbtb11鋅指蛋白913抗體
xy-13557R    ZBT24鋅指蛋白450抗體
xy-13560R    ZA20D3鋅指蛋白20D3抗體
xy-13553R    ZBED3鋅指蛋白BED3抗體
xy-13572R    ZBTB38鋅指蛋白ZBTB38抗體
xy-13562R    ZADH2鋅結合乙醇脫氫酶結構域蛋白2抗體
xy-13567R    ZBTB3鋅指蛋白ZBTB3抗體
xy-13551R    ZBBX鋅指蛋白ZBBX抗體
xy-12253R    ZFP219鋅指蛋白219抗體
xy-12254R    ZFP36L1EGF應答因子1抗體抗體
xy-12255R    phospho-ZFP36L1(Ser334)磷酸化鋅指蛋白36抗體
xy-12240R    ZNF347鋅指蛋白347抗體
xy-13555R    ZBED5鋅指蛋白BED5抗體
xy-12241R    ZNF704鋅指蛋白704抗體
xy-13586R    ZNF434宮頸癌抑癌蛋白5/鋅指蛋白434抗體
xy-0354R    ZCWCC1ZCWCC1抗體
xy-0628R    ZNF300鋅指蛋白300抗體
xy-13573R    ZBTB39鋅指蛋白ZBTB39抗體