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卵透明帶糖蛋白1抗體

英文名稱 ZP1
中文名稱 卵透明帶糖蛋白1抗體
別    名 MGC87693; Processed zona pellucida sperm-binding protein 1; zona pellucida glycoprotein 1 (sperm receptor); Zona pellucida glycoprotein 1; zona pellucida protein 1; Zp 1; Zp-1; Zp1; ZP1_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  干細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014]

Function:
The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.

Subcellular Location:
Secreted > extracellular space > extracellular matrix and Cell membrane.

Tissue Specificity:
Oocytes.

Post-translational modifications:
Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
O-glycosylated.

Similarity:
Belongs to the ZP domain family.
ZPB subfamily.
Contains 1 P-type (trefoil) domain.
Contains 1 ZP domain.xy-8453R    phospho-Tau protein(Thr181)磷酸化微管相關(guān)蛋白抗體
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xy-4198R    Endothelin B Receptor內(nèi)皮素B受體抗體
xy-4220R    TBLR1轉(zhuǎn)導(dǎo)素β1X連鎖受體蛋白1抗體
xy-4223R    TRAP220甲狀腺受體相關(guān)蛋白220抗體
xy-5700R    phospho-TRAP220(Thr1457) 磷酸化甲狀腺受體相關(guān)蛋白220抗體
xy-6116R    TUSC5抑癌基因5抗體
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xy-10107R    phospho-Tau protein(Ser739)磷酸化微管相關(guān)蛋白抗體
xy-10108R    phospho-Tau protein (Ser579)磷酸化微管相關(guān)蛋白抗體
xy-10109R    phospho-Tau protein(Ser531)磷酸化微管相關(guān)蛋白抗體
xy-10110R    phospho-Tau protein(Ser516)磷酸化微管相關(guān)蛋白抗體
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xy-10112R    phospho-Tau protein(Thr529)磷酸化微管相關(guān)蛋白抗體
xy-10113R    phospho-Tau protein(Thr522)磷酸化微管相關(guān)蛋白抗體
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