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鋅指蛋白289抗體

英文名稱 ZNF289/ARFGAP2
中文名稱 鋅指蛋白289抗體
別    名 ADP-ribosylation factor GTPase-activating protein 2; ARF GAP 2; ARFG2_HUMAN; ARFGAP2; FLJ14576; FLJ26000; GTPase activating protein ZNF289; GTPase-activating protein ZNF289; IRZ; Nbla10535; Zfp289; Zinc finger protein 289; Zinc finger protein 289 ID1 regulated; ZNF 289.

說 明 書 0.2ml  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF289/ARFGAP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
ZNF289 functions as a GTPase-activating protein (GAP) for ARF family proteins. Localizing to the cytoplasmic side of the Golgi apparatus, ZNF289 contains one ARF-GAP domain and is found associated with COP-I-coated vesicles.

Function:
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.

Subunit:
Interacts with the coatomer complex. Interacts with the C-terminal appendage domain of COPG1.

Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.xy-1253xy    AQP3(aquaporin 3)水通道蛋白-3抗原
xy-0173xy    IRS-2 胰島素受體底物-2（抗原）
xy-1506xy    AQP1(Aquaporin1)水通道蛋白-1抗原
xy-0186xy    IRS-3胰島素受體底物-3（抗原）
xy-0187xy    IRS-4胰島素受體底物-4（抗原）
xy-0242xy    IRS P53 (Insulin receptor substrate P53)(多肽)
xy-2639xy    PGE2 peptide前列腺素E2抗原
xy-0342xy    Integrin Beta chain (ITG- Beta3/ITGB3)整合素-β3（抗原）
xy-2060xy    AQP9(aquaporin Protein-9)水通道蛋白-9抗原 (多肽抗原)
xy-0108xy    Leptin瘦素（多肽抗原）
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xy-0101xy    M2-PK ( pyruvate Kinase M2)丙酮酸激酶-M2（抗原）
xy-0102xy    M2-PK ( pyruvate Kinase M2 )丙酮酸激酶-M2（抗原）
xy-2201xy    p-Arhgef2/GEF-H1(Rho guanine nucleotide exchange factor 2,pSer810)磷酸化Rho鳥苷酸交換因子2抗原
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xy-0857xy    Beta-arrestin 1/2(beta-arrestin 1/2)β-抑制蛋白1/2抗原
xy-0801xy    ARIP2B(Activin receptor 2B)激活素受體2B/激活素受體相互作用蛋白2b抗體
xy-0027xy    MTR-1A (Melatonin receptor-1A)褪黑素受體（抗原）
xy-0334xy    MTLC (c-Myc target from laryngeal cancer cells)又稱：MYC致癌基因（抗原）
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xy-0008xy    Nestin巢蛋白（神經(jīng)上皮干細(xì)胞蛋白）（抗原）
xy-1155xy    ASCL1/MASH1(Achaete-scute homolog 1)神經(jīng)母細(xì)胞特異性轉(zhuǎn)移因子抗原
xy-1282xy    ASPP1(apoptosis stimulating protein of P53 1)p53凋亡刺激蛋白1抗原
xy-1283xy    ASPP2(apoptosis stimulating protein of P53 2)P53凋亡刺激蛋白2抗原