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鋅指蛋白406抗體

英文名稱 ZFAT/ZNF406
中文名稱 鋅指蛋白406抗體
別    名 AITD3; KIAA1485; MGC126815; MGC126817; ZFAT; ZFAT zinc finger 1; ZFAT_HUMAN; ZFAT1; zinc finger and AT hook domain containing; Zinc finger gene in AITD susceptibility region; zinc finger gene in autoimmune thyroid disease; Zinc finger protein 406; Zinc finger protein ZFAT; ZNF406;
 
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  淋巴細(xì)胞  t-淋巴細(xì)胞  b-淋巴細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 139kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZFAT/ZNF406
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]

Function:
May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.

Subcellular Location:
Nucleus. Cytoplasm > cytosol.xy-1407xy    HIF-1 Beta/ARNT1(Hypoxia-inducible factor-1 Beta)缺氧誘導(dǎo)因子1β 抗原
xy-1447xy    HIF-2 Alpha (Hypoxia-inducible factor-2 Alpha)缺氧誘導(dǎo)因子2α 抗原
xy-0931xy    Histone H1b(Histone H1.4)組蛋白H1b抗原
xy-1414xy    HDAC1/HD1(histone deacetylase 1)組織蛋白去乙?；?抗原
xy-0879xy    Flag-Tag (CT)Flag Tag標(biāo)簽多肽
xy-0965xy    DYKDDDDK Tag(CT)/Flag-Tag標(biāo)簽DYKDDDDK Tag分支肽
xy-2107xy    T7 tag(recombinant T7-tagged proteins)T7 tag標(biāo)簽抗原
xy-2109xy    V5 tag(recombinant V5-tagged protein)V5 tag多肽抗原
xy-2112xy    KT3 tagKT3 tag標(biāo)簽抗原
xy-2110xy    VSV-G tag(vesicular stomatitis virus glycoprotein)VSV-G tag標(biāo)簽抗原
xy-1198xy    HLA-DR(human leukoyte Antigen DR)HLA-DR抗原
xy-1279xy    HLA-E人類白細(xì)胞抗原E
xy-1030xy    Anti-HMGA1 (high mobility group AT-hook 1)高遷移率族蛋白A1抗原
xy-0556xy    HMGA2 (high mobility group A2)高遷移率族蛋白A2抗原
xy-0827xy    HO-1/HSP32 (Hemeo xygenase 1)血紅素氧合酶-1/熱休克蛋白-32抗原
xy-2075xy    HO-1/HSP32(Hemeo xygenase 1)血紅素氧合酶-1/熱休克蛋白-32抗原
xy-1238xy    HO-2(Heme oxygenase 2)血紅素氧合酶-2抗原
xy-0928xy    phospho-HP1/heterochromatin protein 1 (pTyr24)(fruit fly)異染色質(zhì)蛋白1(磷酸化多肽)
xy-0930xy    phospho-heterochromatin protein 1 (pTyr41)peptide異染色質(zhì)蛋白1（磷酸化多肽）
xy-0991xy    HPV18 E6人類乳頭狀瘤病毒18E6
xy-0992xy    HPV16-E7/E7 protein(Human papillomavirus type 16)人類乳頭狀瘤病毒16抗原
xy-1808xy    Hpt/HP(haptoglobin)結(jié)合珠蛋白/觸珠蛋白抗原
xy-1071xy    H-ras/Ras/Ras p21 peptide原癌基因H-ras抗原
xy-1409xy    HSTF2/HSF2 peptide熱休克轉(zhuǎn)錄因子2抗原
xy-2145xy    Hrasls3/HREV107(HRAS like suppressor 3)HRAS樣抑制因子3抗原
xy-1538xy    HSP47(Heat shock protein-47)熱休克蛋白-47抗原
xy-0889xy    HSP-90 Alpha(Heat Shock Protein 90 Alpha )熱休克蛋白90α抗體
xy-1387xy    HSP-105 (heat sock protein-105)熱休克蛋白HSP105抗原
xy-1271xy    HtrA2/Omi peptide絲氨酸蛋白酶/線粒體絲氨酸蛋白酶多肽抗原
xy-1363xy    Iba-1(Ionized calcium bindingadaptor molecule-1)離子鈣接頭蛋白抗原
xy-0898xy    IFABP(Intestinal Fatty acid binding protein)小腸型脂肪酸結(jié)合蛋白抗原
xy-1031xy    IFITM1 (interferon induced transmembrane protein 1)干擾素誘導(dǎo)跨膜蛋白1抗原
xy-1578xy    human IFN- Alpha (Interferon Alpha )干擾素-α抗原（人）
xy-1463xy    IFNGR1/CD119 peptide干擾素-gamma受體1抗原
xy-1108xy    IGFBP-2 (Insulin-like Growth Factor Binding Protein 2)胰島素樣生長因子結(jié)合蛋白-2（多肽）
xy-1434xy    IGFBP-3 (Insulin-like Growth Factor Binding Protein 3)C-term胰島素樣生長因子結(jié)合蛋白-3抗原
xy-1312xy    IGF-IIBP3(Insulin like growth factor 2 mRNA binding protein 3)胰島素樣生長因子2 mRNA 結(jié)合蛋白3抗原
xy-1156xy    IKB Beta (Inhibitor of KB)KB抑制蛋白β(多肽)
xy-1287xy    IKB Alpha (Inhibitor of KB Alpha)KB抑制蛋白α抗原
xy-0767xy    IL-12(Interleukin-12)白介素12抗原（白細(xì)胞介素-12）
xy-1789xy    IL-12(Interleukin-12)human peptide白介素12抗原(人)