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鋅指蛋白161抗體

英文名稱 ZFP161
中文名稱 鋅指蛋白161抗體
別    名 HZF5; MGC126126; ZBTB14; ZF161_HUMAN; ZF5; Zfp 161; Zfp-161; Zfp-5; Zfp161; Zinc finger and BTB domain containing protein 14; Zinc finger and BTB domain-containing protein 14; Zinc finger protein 161 homolog (mouse); Zinc finger protein 161 homolog; Zinc finger protein 478; Zinc finger protein 5; Zinc finger protein 5 homolog; Zinc finger protein homologous to Zfp161 in mouse; ZNF478.
   
說 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZFP161
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
ZFP161 is a 449 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to distinct regions within the nucleus, ZFP161 functions both as a transcriptional repressor of Thymidine Kinase (TK) and c-Myc promoters and as a transcriptional activator of the dopamine transporter (DAT) promoter. ZFP161 contains one BTB (POZ) domain and five C2H2-type zinc fingers which direct its specific localization and nucleic acid binding, respectively. Defects in the gene encoding ZFP161 may be associated with holoprosencephaly type 4 (HPE4), a structural anomaly of the brain characterized by a flattened nasal tip with no visible septum, hypoorism, lack of nasal bridge, ptosis of the left upper eyelid and, in some cases, infant death.

Function:
Transcriptional repressor of MYC and thymidine kinase promoters (By similarity). Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'.xy-1068xy    NR1/NMDAR1(N-Methyl-d-Asprtate receptor 1)谷氨酸受體1（多肽）
xy-2030xy    NR1/NMDAR1/GLUR1(N-Methyl-d-Asprtate receptor 1)谷氨酸受體1抗原
xy-2175xy    NR1/NMDAR1谷氨酸受體1
xy-1067xy    NR2C/NMDAR2C(N-Methyl-d-Asprtate receptor 2C)谷氨酸受體2C（多肽）
xy-1146xy    N-ras原癌基因抗原
xy-1074xy    Nrf2 peptide核因子2相關(guān)因子2抗原
xy-1342xy    NRF-1(nuclear respiratory factor-1)核呼吸因子-1抗原
xy-1958xy    NTCP(Na+/taurocholate Cotransporting Polypeptide)鈉離子/牛磺膽酸共轉(zhuǎn)運(yùn)蛋白抗原
xy-1375xy    Ghrelin 28腦腸肽28
xy-1495xy    OCLN(Occluding)咬合蛋白抗原
xy-1111xy    Oct-4(Octamer-4)胚胎干細(xì)胞關(guān)鍵蛋白抗原
xy-1294xy    ODC(Ornithine decarboxylase)鳥氨酸脫羧酶抗原
xy-2086xy    ompF(putative outer membrane porin F protein)小腸結(jié)腸炎耶爾森氏菌膜通道蛋白抗原
xy-2173xy    OLFM1 peptide嗅球蛋白1多肽抗原
xy-1181xy    ORX-A(orexin-A)增食欲素-A/欲激素A抗原
xy-1314xy    OTR(oxytocin receptor)縮宮素受體
xy-1095xy    OXR (Orexin receptor)食欲素受體(多肽)
xy-1483xy    P2P-R/RBBP6(proliferation potential protein related)增殖潛能相關(guān)蛋白抗原
xy-0534xy    P19ARFp19ARF抑癌基因抗原
xy-2210xy    phospho-p38 ERK/MAPK14 (pThr180/pTyr182) peptide磷酸化絲裂原活化蛋白激酶p38抗原
xy-1689xy    MKK3(MAP Kinase Kinase 3)絲裂原活化蛋白激酶MKK3/6抗原
xy-2090xy    P53(wt-p53)腫瘤抑制基因抗原（野生型P53）
xy-0913xy    Mtp53(Mutant type p53)突變型P53抗原
xy-0942xy    WIG-1(wtp53-induced gene 1)野生型p53誘導(dǎo)基因1抗原
xy-1346xy    P73 proteinP73腫瘤抑制基因抗原
xy-1426xy    p70 S6 Kinase/P70 Beta1p70S6Kb抗原
xy-0588xy    PALB2(partner and locaizer of BRCA2)乳腺癌易感基因相關(guān)蛋白2
xy-1478xy    PAFR/PTAFR血小板活化因子受體抗原
xy-2270xy    Phospho-PAK4 (Ser99) peptide磷酸化p21激活激酶4多肽抗原
xy-0655xy    PAK7/PAK5/MBT激活激酶PAK7/PAK5抗原
xy-0828xy    PAR-1 (Protease-activated receptors-1)蛋白酶激活受體-1抗原
xy-1178xy    PAR-2 (Protease-activated receptors-2)蛋白酶激活受體-2抗原
xy-1196xy    PAR4 (protease-activated receptor 4)蛋白酶活化受體4/前列腺細(xì)胞凋亡反應(yīng)蛋白4抗原
xy-2138xy    PARP(poly ADP-ribose polymerase)N-Terminus多腺苷二磷酸多聚酶抗原(N端)
xy-1201xy    PAX8(Paired box gene 8)配對盒基因8抗原
xy-1102xy    PAX9(Paired box gene 9)配對盒基因9抗原
xy-1159xy    P-cadherin(placental)P-鈣粘附分子抗原
xy-1617xy    LI-cadherin(liver-intestine cadherin)肝腸鈣粘連蛋白抗原
xy-1608xy    PDCD4(programmed cell death 4)凋亡相關(guān)蛋白4抗原
xy-1333xy    TFAR19(TF-1 cell apoptsis-related gene 19)凋亡相關(guān)蛋白TFAR19抗原