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ZC3H7A蛋白抗體

英文名稱 ZC3H7A
中文名稱 ZC3H7A蛋白抗體
別    名 HSPC055; ZC3H7; ZC3HDC7; zinc finger CCCH type containing 7; zinc finger CCCH type containing 7A; zinc finger CCCH type domain containing 7; zinc finger protein AY163807.
  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZC3H7A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
ZC3H7A is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.xy-0716xy    CIDEB peptideCIDEB抗原
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