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鋅指蛋白392抗體

英文名稱 ZSCAN16/ZNF392
中文名稱 鋅指蛋白392抗體
別    名 dJ265C24.3; FLJ22191; Zinc finger and SCAN domain containing protein 16; Zinc finger protein 392; Zinc finger protein 435; ZNF392; ZNF435.

說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZSCAN16/ZNF392
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

PubMed PubMed
產(chǎn)品介紹 background:
Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Zinc finger and SCAN domain-containing protein 16 (ZSCAN16), also known as ZNF392 or ZNF435, is a 348 amino acid member of the Kr黳pel C2H2-type zinc finger protein family. Localized to the nucleus, ZSCAN16 contains four C2H2-type zinc fingers at the carboxy terminus and one SCAN box domain, a leucine rich region of about 80 amino acids, at the amino terminus through which it is thought to be involved in DNA-binding and transcriptional regulation. ZSCAN16 has been shown to repress reporter gene transcription, and overexpression of ZNF435 also suppressed the transcriptional activities of AP-1? Because AP-1?is activated by MAPK-mediated phosphorylation, ZNF435 is though to be involved in the MAPK pathway.

Function:
ZSCAN16, or Zinc finger and SCAN domain containing protein 16, may be involved in transcriptional regulation. 

Subcellular Location:
Nuclear

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 4 C2H2-type zinc fingers.
Contains 1 SCAN box domainxy-9349R    Proteasome 19S S7蛋白酶體PRS7抗體
xy-9350R    Proteasome 20S C2蛋白酶體PSMα1抗體
xy-9351R    Proteasome 20S alpha 2蛋白酶體PSMα2抗體
xy-9355R    Proteasome 20S alpha 6蛋白酶體PSMα6抗體
xy-9356R    PSMA7蛋白酶體PSMα7抗體
xy-9612R    PIBF1孕酮誘導(dǎo)阻斷因子1抗體
xy-9623R    PARP16多腺苷二磷酸多聚酶16抗體
xy-9605R    PITX2成對樣同源結(jié)構(gòu)域轉(zhuǎn)錄因子2抗體
xy-6972R    RNA polymerase IIRNA聚合酶II抗體
xy-1364R    PHLDA1T淋巴細胞凋亡相關(guān)蛋白TDAG51抗體
xy-1372R    PSMD9蛋白酶調(diào)解因子9抗體
xy-8543R    Pancreatic hormone胰腺激素抗體
xy-9844R    PLGLB2纖溶酶相關(guān)蛋白B2抗體
xy-9435R    PAPOL A+B+G多聚合酶α/β/γ抗體
xy-11198R    ProSAPiP1 含脯氨酸突觸相關(guān)蛋白相互作用蛋白1抗體
xy-11197R    PRPH2外周蛋白2抗體
xy-11176R    Pregnancy zone protein妊娠區(qū)帶蛋白PZP抗體
xy-9548R    PGGT1B蛋白香葉烯基轉(zhuǎn)移酶1β（FTβ）抗體
xy-11134R    PCDHB15原鈣粘蛋白15抗體
xy-11136R    PCDHB2原鈣粘蛋白β2抗體
xy-11138R    PCDHB4原鈣粘蛋白β4抗體
xy-11143R    PCDHGA10原鈣粘蛋白γ10抗體
xy-11144R    PCDHGA4原鈣粘蛋白γA4抗體
xy-11145R    PCDHGA2原鈣粘蛋白γA2抗體
xy-11147R    PCDHGA5原鈣粘蛋白γA5抗體
xy-11148R    PCDHGA7原鈣粘蛋白γA7抗體
xy-11149R    PCDHGA8原鈣粘蛋白γA8抗體
xy-11150R    PCDHGA9原鈣粘蛋白γA9抗體
xy-11151R    PCDHGA11原鈣粘蛋白γA11抗體
xy-11152R    PCDHGA12原鈣粘蛋白γA12抗體.