ZRANB1蛋白抗體 返回列表頁

ZRANB1蛋白抗體

英文名稱 ZRANB1
中文名稱 ZRANB1蛋白抗體
別    名 DKFZp762P2216; hTrabid; Trabid; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; ZRAN1_HUMAN; ZRANB1.
  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZRANB1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
TRABID is a 708 amino acid cytoplasmic and nuclear protein that is widely expressed. Belonging to the peptidase C64 family, TRABID is considered a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. TRABID acts by deubiquitinating APC, a negative regulator of Wnt-mediated transcription. TRABID contains a OTU domain, which mediates the deubiquitinating activity, and three RanBP2-type zinc fingers that mediate the specific interaction with 'Lys-63'-linked ubiquitin. It is suggested that TRABID may also modulate TNF?signaling. The gene encoding TRABID is located on chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

Function:
Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.

Subcellular Location:
Cytoplasm. Nucleus.xy-3538R    PSD93突觸后密度蛋白93抗體
xy-3348R    Phospho-PSD93 (Tyr340)磷酸化突觸后密度蛋白93抗體
xy-3349R    Phospho-PSD95 (Tyr236 + Tyr240)磷酸化突觸后密度蛋白95抗體
xy-3350R    Phospho-PTEN(Ser380)磷酸化腫瘤抑制基因PTEN抗體
xy-3351R    Phospho-PTEN(Ser380 + Thr382 + Thr383)磷酸化腫瘤抑制基因PTEN抗體
xy-3539R    Paxillin樁蛋白Paxillin抗體
xy-3352R    Phospho-Paxillin (Tyr118)磷酸化樁蛋白Paxillin抗體
xy-3540R    PIM1絲氨酸/蘇氨酸激酶蛋白Pim1抗體
xy-3353R    Phospho-PIM1(Tyr218)磷酸化前病毒整合位點(diǎn)蛋白1抗體
xy-3541R    Pin1肽基脯氨酞順反異構(gòu)酶Pinl抗體
xy-3354R    Phospho-Pin1 (Ser16)磷酸化肽基脯氨酞順反異構(gòu)酶Pinl抗體
xy-3356R    Phospho-Progesterone Receptor(Ser190)磷酸化孕激素受體抗體
xy-6417R    phospho-PI3 Kinase p110 beta(Ser1070)磷酸化磷脂酰肌醇激酶（PI3Kβ）抗體
xy-6418R    phospho-PP2A alpha (Tyr307)磷酸化蛋白磷酸酶2A（PP2Aα）抗體
xy-7918R    PLK5絲氨酸/蘇氨酸蛋白激酶5抗體
xy-7898R    PICK1蛋白激酶Cα相互作用蛋白1抗體
xy-8065R    PID1磷酸相互作用結(jié)構(gòu)域蛋白1抗體
xy-7931R    PPP2R1A蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基1A抗體
xy-7932R    PPP2R1B蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基1B抗體
xy-7933R    PPP2R3A蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基3A抗體
xy-7929R    PPM1B蛋白質(zhì)磷酸酶1B抗體（PP2Cβ）
xy-7930R    PPM1G蛋白質(zhì)磷酸酶1G抗體（PP2Cγ）
xy-8633R    PFK16磷酸果糖激酶1抗體
xy-11686R    PROSAAS枯草溶菌素轉(zhuǎn)化酶1抑制劑抗體
xy-11687R    PROSAAS枯草溶菌素轉(zhuǎn)化酶1抑制劑抗體
xy-11991R    PPP2R5C蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基5C/PP2A-B56-γ抗體
xy-11992R    PPP2R5D蛋白質(zhì)磷酸酶2調(diào)節(jié)亞基5D/PP2A-B56-δ抗體
xy-11994R    Phosphoserine/threonine磷酸化絲氨酸/蘇氨酸抗體
xy-11985R    PMCA3ATP酶鈣離子轉(zhuǎn)運(yùn)蛋白PMCA3抗體
xy-11218R    Pumilio 1PUM1蛋白抗體
xy-11220R    PTBP1核糖核酸結(jié)合蛋白1抗體