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鋅指蛋白855抗體

英文名稱 ZBTB48
中文名稱 鋅指蛋白855抗體
別    名 0610011D15Rik; AI327031; GLI Kruppel family member HKR3; HKR3; Krueppel related zinc finger protein 3; Krueppel-related zinc finger protein 3; OTTMUSP00000031803; pp9964; Protein HKR3; RP23-445E20.3; ZBT48_HUMAN; ZBTB 48; Zbtb48; Zinc finger and BTB domain containing 48; Zinc finger and BTB domain containing protein 48; Zinc finger and BTB domain-containing protein 48; Zinc finger protein 855; ZNF855.
   
說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBTB48/ZNF855
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 48 (ZBTB48), also known as Kruppel-related zinc finger protein 3 or HKR3, is a 688 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB48 is expressed in the adrenal gland and neuroblastoma cell lines. ZBTB48 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB48 functions as a transcription regulator.

Function:
Binds to and regulates the J and/or S elements in MHC II promoter.

Subcellular Location:
Nucleus.xy-1221R    Rad51Rad51抗體
xy-0251R    RAR alpha維甲酸受體RAR α/RAR α抗體
xy-0516R    RAR Beta維甲酸受體β抗體
xy-1234R    RASSF1ARas相關(guān)區(qū)域家族1A抗體
xy-0795R    Resistin抵抗素抗體
xy-1180R    RhoARhoA抗體
xy-1205R    ROCK2Rho相關(guān)蛋白激酶2抗體
xy-2467R    STAT4信號(hào)轉(zhuǎn)導(dǎo)和轉(zhuǎn)錄激活因子4抗體
xy-2504R    ROS1活性氧簇ROS抗體
xy-5698R    phospho-RAC1(Ser71)磷酸化細(xì)胞遷移誘導(dǎo)因子5抗體
xy-5692R    Phospho-RelB(Ser573)磷酸化核轉(zhuǎn)錄因子NFKB-RelB蛋白抗體
xy-5695R    phospho-RPH3AL(Ser232)磷酸化Ras相關(guān)GTP結(jié)合蛋白抗體
xy-4185R    RelB轉(zhuǎn)錄因子RelB蛋白抗體
xy-4182R    RPA32復(fù)制因子A蛋白2
xy-5693R    phospho-RPA2(Thr21)磷酸化復(fù)制因子A蛋白2抗體
xy-4183R    RPH3ALRas相關(guān)GTP結(jié)合蛋白抗體
xy-5690R    phospho-Rab24(Ser95)磷酸化ras基因相關(guān)蛋白R(shí)ab24抗體
xy-5691R    phospho-Rab24(Tyr17)磷酸化ras基因相關(guān)蛋白R(shí)ab24抗體
xy-5687R    phospho-RGS19(Ser24)磷酸化G蛋白信號(hào)轉(zhuǎn)導(dǎo)調(diào)節(jié)因子19抗體
xy-5688R    phospho-RGS19(Ser151)磷酸化G蛋白信號(hào)轉(zhuǎn)導(dǎo)調(diào)節(jié)因子19抗體
xy-5682R    phospho-RPS6KA1(Ser352)磷酸化絲氨酸/蘇氨酸激酶p90RSK蛋白抗體
xy-5684R    phospho-RAD51(Tyr315)磷酸化Rad51抗體
xy-5685R    phospho-RUNX2(Ser451)磷酸化成骨特異性轉(zhuǎn)錄因子抗體
xy-5689R    phospho-RGS19(Tyr143)磷酸化G蛋白信號(hào)轉(zhuǎn)導(dǎo)調(diào)節(jié)因子19抗體
xy-3867R    RGS19G蛋白信號(hào)轉(zhuǎn)導(dǎo)調(diào)節(jié)因子19抗體
xy-6142R    RING1環(huán)指蛋白1抗體
xy-4132R    MST1R原癌基因c-Met相關(guān)酪氨酸激酶抗體
xy-5489R    phospho-Ron(Ser1349)磷酸化原癌基因c-Met相關(guān)酪氨酸激酶抗體
xy-5795R    Robo4腫瘤血管內(nèi)皮調(diào)節(jié)蛋白R(shí)obo4抗體
xy-5794R    Robo軸突導(dǎo)向受體抗體
xy-1560R    Reelin絡(luò)絲蛋白抗體