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當前位置:上海信裕生物科技有限公司>>抗體>>一抗>> 鋅指蛋白ZBTB7C抗體
產(chǎn)品型號
品 牌Abcam
廠商性質生產(chǎn)商
所 在 地上海
更新時間:2015-06-04 15:01:22瀏覽次數(shù):294次
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英文名稱 ZBTB7C
中文名稱 鋅指蛋白ZBTB7C抗體
別 名 APM 1; APM1; B230208J24Rik; FLJ37907; ZBTB36; Zinc finger and BTB domain containing 7C.
說 明 書 0.2ml
研究領域 轉錄調節(jié)因子 鋅指蛋白 表觀遺傳學
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep,
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 69kDa
細胞定位 細胞核
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBTB7C
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Zinc finger and BTB domain-containing protein 7C (ZBTB7C), also designated affected by papillomavirus DNA integration in ME180 cells protein 1 (APM-1), contains 1 BTB (POZ) domain and 4 C2H2-type zinc fingers. ZBTB7C is detected in normal cervical keratinocytes and may be a potential tumor suppressor gene against human papillomavirus (HPV) mediated cervical carcinogenesis.
Function:
The function of Anti-ZBTB7C has not yet been determined.
Tissue Specificity:
Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines.
Similarity:
Contains 1 BTB (POZ) domain.
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