鋅指蛋白206抗體 返回列表頁

鋅指蛋白206抗體

英文名稱 ZNF206
中文名稱 鋅指蛋白206抗體
別    名 Zfp206; Zinc finger and SCAN domain-containing protein 10; Zinc Finger Protein 206; ZSCAN10; ZSC10_HUMAN.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF206
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF206 (zinc finger protein 206), also known as ZSCAN10 (zinc finger and SCAN domain containing 10), is a 725 amino acid protein that contains one SCAN box domain and 14 C2H2-type zinc fingers. Localized to the nucleus, ZNF206 is thought to play a role in transcriptional regulation events. The gene encoding ZNF206 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Function:
Znf206 is a zinc finger protein and probable transcriptional regulator. It is expressed in embryonic stem cells and downregulated upon differentiation. Both Oct4 and Sox2 bind the znf206 gene.

Subunit:
Interacts with POU5F1/OCT4 and SOX2 (By similarity).xy-5634R    phospho-SIRT6(Ser338)磷酸化沉默調(diào)節(jié)相關(guān)蛋白6抗體
xy-5635R    phospho-SNAI2 (Ser155+Ser158+Ser160+Tyr163+Tyr168)磷酸化鋅指轉(zhuǎn)錄因子Slug抗體
xy-5637R    phospho-SLC29A4 (Tyr198)磷酸化腦質(zhì)膜單胺轉(zhuǎn)運蛋白PMAT抗體
xy-4175R    SYT6突觸蛋白6抗體
xy-4176R    SLC29A4腦質(zhì)膜單胺轉(zhuǎn)運蛋白PMAT抗體
xy-3896R    SOD4超氧化物歧化酶4抗體
xy-3913R    SLCO2B1可溶性載質(zhì)轉(zhuǎn)運蛋白2B1抗體
xy-5304R    phospho-Separase (Ser1073)磷酸化外紡錘體極樣蛋白1抗體
xy-5844R    SMAGP小細胞跨膜糖化蛋白抗體
xy-6685R    SCN10A鈉通道蛋白10α抗體
xy-5754R    SP17精子表面蛋白Sp17抗體
xy-4566R    SPRN新朊蛋白抗體（C端）
xy-4252R    SCNN1B上皮鈉通道β抗體
xy-5701R    phospho-SCNN1B(Thr615)磷酸化上皮鈉通道β2抗體
xy-5702R    phospho-SCNN1B(Ser633) 磷酸化上皮鈉通道β2抗體
xy-1248R    S100BS100B蛋白抗體
xy-6692R    Sema3C跨膜蛋白Sema3C抗體
xy-6693R    Serca2肌漿/內(nèi)質(zhì)網(wǎng)鈣ATP酶2抗體
xy-1602R    SPA-1信號感應(yīng)增殖相關(guān)蛋白1抗體
xy-1309R    Syndecan-1多配體蛋白聚糖1抗體
xy-0921R    SIRT1沉默調(diào)節(jié)蛋白1抗體
xy-2660R    Slc26a5感覺神經(jīng)性耳聾常染色體隱性遺傳61抗體
xy-1897R    Synaptotagmin-4突觸結(jié)合蛋白4抗體
xy-1899R    SRG11/Spata17睪丸凋亡基因抗體
xy-1898R    SPATA12睪丸特異表達新基因5抗體
xy-0473R    SLC1A5溶質(zhì)攜帶物家族-1抗體
xy-6770R    STK17A絲氨酸/蘇氨酸蛋白激酶17A/DAP凋亡誘導(dǎo)蛋白激酶1抗體
xy-1530R    Slc4a7碳酸氫鈉協(xié)同轉(zhuǎn)運蛋白4-A7抗體
xy-9463R    SYNC微管卷曲蛋白SYNC抗體
xy-3398R    Phospho-SHIP1 (Tyr1020)磷酸化SH2結(jié)構(gòu)含磷酸肌醇SHIP1抗體
xy-3393R    Phospho-SIRT1(Ser47)磷酸化沉默調(diào)節(jié)蛋白1抗體