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鋅指蛋白46抗體

英文名稱 ZBTB25
中文名稱 鋅指蛋白46抗體
別    名 ZBT25_HUMAN; ZBTB25; Zinc finger and BTB domain-containing protein 25; Zinc finger protein 46; Zinc finger protein KUP.
  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBTB25/ZNF46
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 25 (ZBTB25), also known as ZNF46 or KUP, is a 435 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus and expressed mainly in hematopoietic cells and testis, ZBTB25 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB25 functions as a transcription regulator. 

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed mainly in hematopoietic cells and testis.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 2 C2H2-type zinc fingers.xy-13581R    ZBTB5鋅指蛋白ZBTB5抗體
xy-13582R    ZBTB6鋅指蛋白ZBTB6抗體
xy-13583R    ZBTB7C鋅指蛋白ZBTB7C抗體
xy-13584R    ZBTB8A鋅指蛋白ZBTB8A抗體
xy-13585R    ZBTB8B鋅指蛋白916B抗體
xy-13574R    ZBTB4鋅指蛋白903抗體
xy-13575R    ZBTB40鋅指蛋白923抗體
xy-6503R    ZNF288鋅指蛋白288抗體
xy-6119R    ZNF185鋅指蛋白185抗體
xy-6120R    ZNF431鋅指蛋白431抗體
xy-6200R    ZNF379鋅指蛋白379抗體
xy-8463R    ZNF804A鋅指蛋白804A抗體
xy-5716R    ZNF693鋅指蛋白693抗體
xy-13570R    ZBTB3鋅指蛋白ZBTB3抗體
xy-9732R    ZWILCH著絲粒ZWILCH蛋白抗體
xy-12252R    ZFP57鋅指蛋白57抗體
xy-12232R    ZNF717鋅指蛋白717抗體
xy-12088R    ZDHHC7鋅指蛋白370抗體
xy-12216R    ZNF3鋅指蛋白3抗體
xy-12220R    ZNF423鋅指蛋白423抗體
xy-12218R    ZNF239鋅指蛋白239抗體
xy-12219R    ZNF426鋅指蛋白426抗體
xy-12222R    phospho-ZNF598(Tyr306)磷酸化鋅指蛋白598抗體
xy-11973R    ZNF423鋅指蛋白423抗體
xy-7782R    zinc finger protein 830鋅指蛋白830抗體
xy-13550R    ZAR1L受精卵抑制蛋白1樣蛋白抗體
xy-10464R    ZNF434宮頸癌抑癌蛋白5/鋅指蛋白434抗體
xy-13577R    ZBTB42鋅指蛋白925抗體
xy-4192R    SLC25A20線粒體二羧酸載體蛋白20抗體
xy-4903R    SLC27A1長鏈脂肪酸轉(zhuǎn)運蛋白1抗體
xy-4215R    Sin3b轉(zhuǎn)錄抑制蛋白Sin3b抗體
xy-4216R    Sphingomyelin Synthase 1鞘磷脂合成酶1抗體