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鋅指蛋白346抗體

英文名稱 ZNF346
中文名稱 鋅指蛋白346抗體
別    名 DKFZp547M223; Double stranded RNA binding zinc finger protein; Double stranded RNA binding zinc finger protein JAZ; JAZ; Just another zinc finger protein; Zfp346; Zinc finger protein 346; ZN346_HUMAN; Znf346.
  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Human ZNF346
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF346 (Zinc finger protein 346), also known as JAZ (Just another zinc finger protein), is a 294 amino acid protein that contains four matrin-type zinc fingers. The matrin-type zinc finger, which is very similar in structure to the classical DNA-binding C2H2 zinc finger, was first identified in the protein matrin-3. The matrin-type zinc finger has also been identified in several spliceosome RNA-binding proteins. Two isoforms exists due to alternate splicing events.

Function:
Binds to dsRNA and DNA.

Subunit:
Forms a heteromeric complex with XPO5 and ILF3. Found in a nuclear export complex with XPO5, RAN, ILF3, ZNF346 and double-stranded RNA. Interacts with XPO5. Interacts with ILF3 in an RNA-independent manner. 

Subcellular Location:
Nucleus Cytoplasm. xy-0374R    Rabbit Anti-horse IgM兔抗馬IgM
xy-0297G    Goat Anti-human IgG羊抗人IgG
xy-0297R    Rabbit Anti-human IgG兔抗人IgG
xy-0360R    Rabbit Anti-human IgA兔抗人免疫球蛋白A
xy-0377R    Rabbit Anti-mouse IgG-Fc兔抗小鼠IgG-Fc
xy-0309R    Rabbit Anti-pig IgG兔抗豬IgG
xy-0309Rs    Rabbit anti-Pig IgG whole serum兔抗豬IgG抗血清
xy-0293Rs    Rabbit anti-Rat IgG whole serum兔抗大鼠IgG抗血清
xy-0293M    Mouse Anti-rat IgG小鼠抗大鼠IgG
xy-0293R    Rabbit Anti-rat IgG兔抗大鼠IgG
xy-0295M    Mouse Anti-rabbit IgG小鼠抗兔IgG
xy-0296R    Rabbit Anti-mouse IgG兔抗小鼠IgG
xy-0335R    Rabbit Anti-Monkey IgG兔抗猴IgG
xy-0346R    Rabbit Anti-rat IgM兔抗大鼠IgM
xy-0369M    Mouse Anti-Rabbit IgM小鼠抗兔IgM
xy-0346Rs    Rabbit anti-Rat IgM whole serum兔抗大鼠IgM抗血清
xy-0295Gs    Goat anti-Rabbit IgG whole serum羊抗兔IgG抗血清
xy-0295xys    Donkey anti-Rabbit IgG whole serum驢抗兔IgG抗血清
xy-0368G    Goat Anti-Mouse IgM羊抗小鼠IgM
xy-0293G    Goat Anti-rat IgG羊抗大鼠IgG
xy-0358G    Goat Anti-Guinea pig IgG羊抗豚鼠IgG
xy-0345G    Goat Anti-human IgM羊抗人IgM
xy-0294M    Mouse Anti-Goat IgG小鼠抗羊IgG
xy-0312R    Rabbit Anti-Avidin兔抗親和素
xy-0311R    Rabbit Anti-Biotin兔抗生物素抗體IgG
xy-0327R    Rabbit Anti-Bovine IgM兔抗牛IgM
xy-0314R    Rabbit Anti-chicken IgM兔抗雞IgM
xy-0303R    Rabbit Anti-dog IgG兔抗狗IgG
xy-0370R    Rabbit Anti-Goat IgM兔抗羊IgM
xy-0358R    Rabbit Anti-Guinea pig IgG兔抗豚鼠IgG
xy-0375R    Rabbit Anti-Guinea pig IgM兔抗豚鼠IgM
xy-0308R    Rabbit Anti-horse IgG兔抗馬IgG
xy-0345R    Rabbit Anti-human IgM兔抗人IgM
xy-0336R    Rabbit Anti-Monkey IgM兔抗猴IgM

Similarity:
Contains 4 matrin-type zinc fingers.