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鋅指/環(huán)指蛋白2抗體

英文名稱 ZNRF2
中文名稱 鋅指/環(huán)指蛋白2抗體
別    名 E3 ubiquitin-protein ligase ZNRF2; Protein Ells2; RING finger protein 202; Zinc/RING finger protein 2; Znrf2; ZNRF2_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNRF2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF2 (zinc and ring finger 2), also known as RNF202, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, as well as the endosome and the cell junction. Expressed at high levels in brain tissue, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity. Upon DNA damage, ZNRF2 is subject to phosphorylation, probably by ATR or ATM.xy-0345G-xyE-xyy3    Goat Anti-human IgM/PE-Cy3PE-Cy3標(biāo)記的羊抗人IgM
xy-0345G-xyE-xyY5    Goat Anti-human IgM/PE-CY5PE-CY5標(biāo)記的羊抗人IgM
xy-0345G-Axyxy    Goat Anti-human IgM/APCAPC標(biāo)記的羊抗人IgM
xy-0345G-AF350    Goat Anti-human IgM/Alexa Fluor 350Alexa Fluor 350標(biāo)記的羊抗人IgM
xy-0345G-AF488    Goat Anti-human IgM/Alexa Fluor 488Alexa Fluor 488標(biāo)記的羊抗人IgM
xy-0345G-AF555    Goat Anti-human IgM/Alexa Fluor 555Alexa Fluor 555標(biāo)記的羊抗人IgM
xy-0345G-AF647    Goat Anti-human IgM/Alexa Fluor 647Alexa Fluor 647標(biāo)記的羊抗人IgM
xy-0345G-xyE-xyy5.5    Goat Anti-human IgM/PE-Cy5.5PE-Cy5.5標(biāo)記的羊抗人IgM
xy-0345G-xyE-xyy7    Goat Anti-human IgM/PE-Cy7PE-Cy7標(biāo)記的羊抗人IgM
xy-0345G-xyy3    Goat Anti-human IgM/Cy3Cy3標(biāo)記的羊抗人IgM
xy-0345G-Axy    Goat Anti-human IgM/AP堿性磷酸酶（AP）標(biāo)記的羊抗人IgM
xy-0345G-HRxy    Goat Anti-human IgM/HRP辣根過氧化物酶標(biāo)記的羊抗人IgM
xy-0297M-HRxy    Mouse Anti-human IgG/HRP辣根過氧化物酶標(biāo)記的小鼠抗人IgG
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xy-0297M-RBITxy    Mouse Anti-human IgG/RBITC羅丹明標(biāo)記的小鼠抗人IgG
xy-0297M-FITxy    Mouse Anti-human IgG/FITCFITC標(biāo)記的小鼠抗人IgG
xy-0297M-Golxy    Mouse Anti-human IgG/Gold膠體金標(biāo)記的小鼠抗人IgG
xy-0297M-xyE-xyy5.5    Mouse Anti-human IgG/PE-Cy5.5PE-Cy5.5標(biāo)記的小鼠抗人IgG
xy-0297M-xyE-xyy7    Mouse Anti-human IgG/PE-Cy7PE-Cy7標(biāo)記的小鼠抗人IgG
xy-0297M-AF350    Mouse Anti-human IgG/Alexa Fluor 350Alexa Fluor 350標(biāo)記的小鼠抗人IgG
xy-0297M-AF488    Mouse Anti-human IgG/Alexa Fluor 488Alexa Fluor 488標(biāo)記的小鼠抗人IgG
xy-0297M-AF555    Mouse Anti-human IgG/Alexa Fluor 555Alexa Fluor 555標(biāo)記的小鼠抗人IgG
xy-0297M-xyE-xyy3    Mouse Anti-human IgG/PE-Cy3PE-Cy3標(biāo)記的小鼠抗人IgG
xy-0297M-xyE-xyY5    Mouse Anti-human IgG/PE-CY5PE-CY5標(biāo)記的小鼠抗人IgG
xy-0297M-Axyxy    Mouse Anti-human IgG/APCAPC標(biāo)記的小鼠抗人IgG
xy-0297M-xyy3    Mouse Anti-human IgG/Cy3Cy3標(biāo)記的小鼠抗人IgG
xy-0297M-xyy5    Mouse Anti-human IgG/Cy5Cy5標(biāo)記的小鼠抗人IgG
xy-0297M-xyy5.5    Mouse Anti-human IgG/Cy5.5Cy5.5標(biāo)記的小鼠抗人IgG
xy-0297M-xyy7    Mouse Anti-human IgG/Cy7Cy7標(biāo)記的小鼠抗人IgG
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xy-0345M-FITxy    Mouse Anti-human IgM/FITCFITC標(biāo)記的小鼠抗人IgM
xy-0345M-xyy3    Mouse Anti-human IgM/Cy3Cy3標(biāo)記的小鼠抗人IgM
xy-0345M-xyy5    Mouse Anti-human IgM/Cy5Cy5標(biāo)記的小鼠抗人IgM
xy-0345M-xyy5.5    Mouse Anti-human IgM/Cy5.5Cy5.5標(biāo)記的小鼠抗人IgM