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鋅指蛋白217抗體

英文名稱 ZNF217
中文名稱 鋅指蛋白217抗體
別    名 zinc finger protein 217; ZABC 1; ZABC1; ZN 217; ZN217; ZNF 217; 4933431C08Rik; AW987152; Gm562; Zfp217; ZN217_HUMAN .

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 115kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF217
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
ZNF217 (Zinc-finger protein 217) is a Kruppel-like zinc-finger protein which functions as a transcriptional repressor protein and forms a complex with a number of proteins including CoREST, BHC110/LSD1, HDAC2 and CtBP1. ZNF217 has been shown to repress E-cadherin promoter activity. ZNF217 is overexpressed in a number of cancers including breast and ovarian. ZNF217 and its associated proteins have been implicated in a novel pathway that is involved in cancer progression.

Function:
Binds to the promoters of target genes and functions as epressor. Promotes cell proliferation and antagonizes cell death. romotes phosphorylation of AKT1 at 'Ser-473'.

Subunit:
Component of a histone deacetylase complex that contains DAC2, KDM1A, CTBP1 and ZNF217. May be a component of a BHC histone eacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, DM1A, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and TF2I. Interacts with CTBP1 and CTBP2.

Subcellular Location:
Nucleus (Probable).xy-1966R    KLK7激肽釋放酶7抗體
xy-1967R    KLK9激肽釋放酶9抗體（舒血管素9）
xy-1968R    KLK14激肽釋放酶14抗體
xy-3656R    KCNA7鉀電壓閥門通道混合器相關(guān)亞家族成員7抗體
xy-2436R    Kir6.2ATP敏感性鉀通道亞基kir6.2抗體
xy-13686R    KAT5TIP60抗體
xy-10166R    KDM1組蛋白賴氨酸特異性脫甲基酶1抗體
xy-6140R    KMT8轉(zhuǎn)錄因子GATA3結(jié)合蛋白G3B抗體
xy-3713R    Phospho-p57 Kip2 (Thr310)磷酸化周期蛋白依賴激酶抑制因子1C抗體
xy-5535R    phospho-Kv2.1(Tyr128)磷酸化鉀通道蛋白DRK1抗體
xy-2712R    KCNC4離子通道蛋白Kv3.4抗體
xy-2587R    KCNC3/Kv3.3離子通道蛋白Kv3.3抗體
xy-12198R    KDM4B組蛋白去甲基化酶JMJD2B抗體
xy-4045R    Ketohexokinase肝果糖激酶抗體
xy-11174R    KY脊柱側(cè)后凸畸形肽酶抗體
xy-5130R    KAT2B組蛋白乙酰轉(zhuǎn)移酶PCAF抗體
xy-5400R    Phospho-c-Kit(Ser741)磷酸化原癌基因c-kit抗體
xy-5401R    Phospho-c-Kit(Ser721)磷酸化原癌基因c-kit抗體
xy-5402R    KCNC1離子通道蛋白Kv3.1抗體
xy-3799R    KLK11激肽釋放酶11抗體
xy-3800R    Kappa Light Chaink輕鏈抗體
xy-6260R    KIST絲氨酸/蘇氨酸蛋白激酶KIST抗體（激酶相互作用與白血病相關(guān)基因）
xy-11027R    KIF5A/NKHC1驅(qū)動(dòng)蛋白KIF5A抗體
xy-8517R    KCC2神經(jīng)細(xì)胞鉀氯離子轉(zhuǎn)運(yùn)蛋白抗體
xy-1033R    KRAS原癌基因K-ras抗體
xy-0749R    Kisspeptin腫瘤轉(zhuǎn)移抑制基因抗體
xy-0225R    KLH血藍(lán)蛋白抗體
xy-9857R    KCNG2心臟鉀離子通道蛋白亞基2抗體
xy-8358R    KLHDC8AKLHDC8A蛋白抗體
xy-4894R    Keratan Sulfate硫酸角質(zhì)素抗體
xy-1577R    KLF13腸道內(nèi)富含的Kruppel樣因子13