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鋅指脂蛋白抗體

英文名稱 ZNF268
中文名稱 鋅指脂蛋白抗體
別    名 zinc finger protein ZNF268; zinc finger protein 268 isoform c; zinc finger protein 3; zinc finger protein HZF3; HZF3; MGC126498; ZN268_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領域 染色質和核信號  信號轉導  轉錄調節(jié)因子  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 108kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF268
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus (Probable).

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family. 
Contains 24 C2H2-type zinc fingers. 
Contains 1 KRAB domain. 

Gene ID:
10795

Database links:

Entrez Gene: 10795 Human

Omim: 604753 Human

SwissProt: Q14587 Human

Unigene: 124047 Human

Important Note:
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