胞質(zhì)緊密粘連蛋白1/閉鎖小帶蛋白1抗體 返回列表頁

胞質(zhì)緊密粘連蛋白1/閉鎖小帶蛋白1抗體

英文名稱 ZO-1
中文名稱 胞質(zhì)緊密粘連蛋白1/閉鎖小帶蛋白1抗體
別    名 ZO1 tight junction protein; Tight junction protein 1; Tight junction protein ZO-1; Tight junction protein ZO1; TJP1; zo-1; Zo1; ZO1_HUMAN; Zona occludens 1; Zona occludens 1 protein; Zona occludens protein 1; Zonula occludens 1 protein; Zonula occludens protein 1.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  細(xì)胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 Flow-Cyt=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 191kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZO-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions.

Function:
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.

Subunit:
Interacts with BVES (via the C-terminus cytoplasmic tail). Interacts with HSPA4 and KIRREL1. Homodimer, and heterodimer with TJP2/ZO-2 and TJP3/ZO-3. Interacts with OCLN, CALM, claudins, CGN/cingulin, CXADR, GJA12, GJD3 and UBN1. Interacts (via ZU5 domain) with CDC42BPB and MYZAP. Interacts (via PDZ domain) with GJA1.xy-1425R    ASK1細(xì)胞凋亡信號調(diào)節(jié)激酶1抗體
xy-5424R    MAP3K7IP3NFKB激活蛋白1抗體
xy-5425R    phospho-MAX protein(Tyr123)磷酸化Myc基因相關(guān)X因子抗體
xy-1484R    MTHFR亞甲基四氫葉酸還原酶MTHFR抗體
xy-1433R    MEK1MEK1/MAPKK1抗體(N-端)
xy-0963R    MTNR1B褪黑素受體1B抗體
xy-1422R    MRP4多藥耐藥相關(guān)蛋白4抗體
xy-1437R    MRP5多藥耐藥相關(guān)蛋白5抗體
xy-1824R    Mitofilin線粒體內(nèi)膜蛋白抗體
xy-1913R    MMP-8基質(zhì)金屬蛋白酶-8/膠原酶2抗體
xy-1853R    MMP-11基質(zhì)金屬蛋白酶11抗體
xy-1854R    MMP-12基質(zhì)金屬蛋白酶-12抗體
xy-1855R    MMP-15基質(zhì)金屬蛋白酶-15抗體
xy-1856R    MMP-16基質(zhì)金屬蛋白酶-16抗體
xy-1862R    MMP-17基質(zhì)金屬蛋白酶-17抗體
xy-1802R    Moesin膜突蛋白抗體
xy-0886R    Measles virus fusion protein麻疹病毒融合蛋白抗體
xy-9522R    MPP1紅細(xì)胞膜蛋白55抗體
xy-9339R    MARCH5膜相關(guān)環(huán)指蛋白5抗體
xy-5481R    phospho-MEF2C(Ser387)磷酸化肌細(xì)胞增強(qiáng)因子2C抗體
xy-13764R    MRP63線粒體核糖體蛋白MRP63抗體
xy-5482R    phospho-MEF2C(Thr20)磷酸化肌細(xì)胞增強(qiáng)因子2C抗體
xy-10250R    MMP13基質(zhì)金屬蛋白酶13抗體
xy-11525R    MICAL1酪氨酸單氧化酶微管相關(guān)蛋白MICAL抗體
xy-11513R    MKS1梅克爾-格魯伯綜合征相關(guān)蛋白抗體
xy-6811R    MUM1突變的黑色素瘤相關(guān)抗原1抗體
xy-6816R    MAGEA10黑色素瘤相關(guān)抗原10抗體
xy-6301R    MAP3K2絲裂原活化蛋白激酶激酶2抗體
xy-6626R    GPR24G蛋白偶聯(lián)受體24抗體
xy-6722R    MAPK organizer 1絲裂原活化蛋白激酶組織蛋白1抗體
xy-6680R    MEIS1同源盒蛋白Meis1抗體
xy-6679R    MAOA單氨氧化酶A抗體
xy-8512R    MSX1MSH同源蛋白1樣蛋白抗體