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斑聯(lián)蛋白抗體

英文名稱 Zyxin
中文名稱 斑聯(lián)蛋白抗體
別    名 ESP 2; ESP2; HED 2; HED2; ZYX; ZYX protein; Zyxin 2; Zyxin2; Zyxin-2; ZYX_HUMAN.

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30/63kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Zyxin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].xy-11419R    MRAP2黑素皮質(zhì)素2受體輔助蛋白2抗體
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xy-4943R    MPO髓過(guò)氧化物酶抗體
xy-11352R    MAGI1膜相關(guān)鳥(niǎo)苷酸反轉(zhuǎn)激酶1抗體
xy-11353R    Munc13 神經(jīng)突觸前膜胞內(nèi)蛋白13抗體
xy-11322R    Membralin高度保守基因相關(guān)蛋白Membralin抗體
xy-11320R    MNX1運(yùn)動(dòng)神經(jīng)元及胰腺同源蛋白1抗體
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xy-3293R    Phospho-Mre11 (Ser676)磷酸化DNA損傷關(guān)鍵蛋白Mre11抗體
xy-3504R    MST1蛋白激酶MST抗體
xy-3294R    Phospho-Mst1(Thr183) + Mst2(Thr180)磷酸化蛋白激酶MST抗體
xy-3295R    Phospho-MYL(Ser19)磷酸化肌球蛋白輕鏈2抗體
xy-3505R    Myt1髓鞘轉(zhuǎn)錄因子1抗體
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xy-9470R    MEF2B肌細(xì)胞增強(qiáng)因子2B抗體
xy-9471R    MESP1心血管發(fā)育中胚層相關(guān)蛋白1抗體
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