WDR35蛋白抗體 返回列表頁

WDR35蛋白抗體

英文名稱 WDR35
中文名稱 WDR35蛋白抗體
別    名 Intraflagellar transport protein 121 homolog; KIAA1336; MGC33196; Naofen; WD repeat domain 35; WD repeat-containing protein 35; WDR35; WDR35_HUMAN.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細胞凋亡  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 133kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WDR35
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximay 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010]

Function:
May promote CASP3 activation and TNF-stimulated apoptosis.

DISEASE:
Defects in WDR35 are the cause of cranioectodermal dysplasia type 2 (CED2) [MIM:613610]. A disorder characterized by craniofacial, skeletal and ectodermal abnormalities. Clinical features include short stature, dolichocephaly, craniosynostosis, narrow thorax with pectus excavatum, short limbs, brachydactyly, joint laxity, narrow palpebral fissures, ecanthus with hyperorism, low-set simple ears, everted lower lip, and short neck. Teeth abnormalities included widely spaced, hypoplastic and fused teeth.xy-5520R    phospho-NF1(Ser2515)磷酸化1型神經(jīng)纖維瘤抗體
xy-4141R    NUDEL中心粒蛋白Nudel抗體
xy-5522R    phospho-NDEL1(Ser231)磷酸化中心粒蛋白Nudel抗體
xy-5088R    NSDHL類固醇脫氫酶樣蛋白NSDHL抗體
xy-8441R    Phospho-NFKB1(Ser373)磷酸化細胞核因子p50/k基因結(jié)合核因子抗體
xy-5521R    phospho-NF1(Ser2817)磷酸化1型神經(jīng)纖維瘤抗體
xy-8448R    Phospho-NMDAR2B (Tyr1474)磷酸化谷氨酸受體2B抗體
xy-5510R    Phospho-NFKB1 (Thr931)磷酸化細胞核因子p50/k基因結(jié)合核因子抗體
xy-5511R    Phospho-NFKB1 (Ser907)磷酸化細胞核因子p50/k基因結(jié)合核因子抗體
xy-5512R    Phospho-NFKB1 (Ser337)磷酸化細胞核因子p50/k基因結(jié)合核因子抗體
xy-5513R    Phospho-NFKB1 (Ser893)磷酸化細胞核因子p50/k基因結(jié)合核因子抗體
xy-5514R    Phospho-NFKBIA (Tyr42) 磷酸化IKB α抗體
xy-5515R    phospho-NFKBIA(Tyr305)磷酸化IKB alpha抗體
xy-5516R    phospho-NFATc2(Ser330)磷酸化核因子活化T細胞胞漿蛋白2抗體
xy-10156R    NOX5還原型輔酶Ⅱ氧化酶5/煙酰胺腺嘌呤二核苷酸磷酸抗體
xy-6314R    NANOS2生殖細胞增殖相關(guān)蛋白NANOS2抗體
xy-3622R    NFKB p52細胞核因子/k基因結(jié)合核因子 p52/p100抗體
xy-3723R    Phospho-NFKB2(Ser866+Ser870)磷酸化細胞核因子/k基因結(jié)合核因子p100抗體
xy-2798R    NAT2N-乙酰基轉(zhuǎn)移酶2抗體
xy-6717R    NALP2富含亮氨酸重復(fù)結(jié)構(gòu)域蛋白2抗體
xy-4636R    NR2C2孤兒核受體TAK1抗體
xy-10227R    Nanos3骨巢蛋白抗體
xy-13710R    Netrin 5軸突生長誘向因子5抗體
xy-2513R    phospho-NFKBIA(Ser32/36)磷酸化p-IκB-α抗體
xy-6079R    G21 proteinG21蛋白質(zhì)抗體
xy-2184R    NQO1醌氧化還原酶抗體
xy-1070R    NPY1R神經(jīng)肽Y1受體抗體
xy-1068R    NMDAR1 谷氨酸受體1抗體
xy-5968R    NARG2谷氨酸受體調(diào)節(jié)蛋白2抗體
xy-6077R    NIT1腈水解酶1抗體
xy-6349R    Nerve growth factor inducible神經(jīng)生長因子誘導(dǎo)蛋白抗體