WD重復蛋白77抗體 返回列表頁

WD重復蛋白77抗體

英文名稱 WDR77
中文名稱 WD重復蛋白77抗體
別    名 2610312E17Rik; Androgen receptor cofactor p44; C79984; HKMT1069; MEP 50; MEP-50; MEP50; MEP50_HUMAN; Methylosome protein 50; MGC2722; Nbla10071; p44; p44/Mep50; RGD1310479; RP11 552M11.3; WD repeat containing protein 77; WD repeat domain 77; WD repeat-containing protein 77; WDR77.
 
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Horse, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WDR77
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM, Mar 2008]

Function:
Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.xy-7665R    NUP50核孔蛋白50抗體
xy-0134R    Nogo-A軸索過度生長抑制因子-A抗體
xy-0156R    nNos/一氧化氮合成酶-1抗體（神經(jīng)型）
xy-0163R    eNOS一氧化氮合成酶-3（內(nèi)皮型）抗體
xy-0181R    Nociceptin receptor孤菲肽受體/痛敏肽受體抗體
xy-0448R    NIS鈉碘轉(zhuǎn)運體蛋白抗體
xy-0064R    Neurokinin 1 ReceptorP物質(zhì)受體抗體
xy-0166R    Neurokin B receptor神經(jīng)激肽B受體抗體
xy-0688R    Nm23腫瘤轉(zhuǎn)移抑制基因抗體
xy-1066R    NME1腫瘤抑制基因抗體
xy-1073R    Nm23-H2腫瘤抑制基因抗體
xy-0075R    Nociceptin孤菲肽/痛敏肽抗體
xy-0129R    Nogo R軸索過度生長抑制因子受體/Nogo受體抗體
xy-12151R    NAV3神經(jīng)元引導蛋白3抗體
xy-10027R    NCR1細胞毒性受體NK-p46抗體
xy-12146R    Neurabin 2神經(jīng)組織特異性F肌動蛋白結合蛋白2抗體
xy-9320R    NYS48NYS48蛋白抗體
xy-9331R    NHLRC1肌痙攣性癲癇病相關EPM2蛋白抗體
xy-9332R    NHLRC2非霍奇金淋巴瘤重復蛋白2抗體
xy-0323R    NMDAR2C谷氨酸受體2C抗體（N端）
xy-6855R    NALP4癌/睪丸抗原58抗體
xy-9333R    NHLRC3非霍奇金淋巴瘤重復蛋白3抗體
xy-9710R    NOP2增殖相關核仁抗原抗體
xy-6864R    NALP12NALP12抗體
xy-6865R    NALP6富含亮氨酸重復結構域蛋白6抗體
xy-6866R    NLRP7富含亮氨酸重復結構域蛋白7抗體
xy-6867R    NLRP9富含亮氨酸重復結構域蛋白9抗體
xy-6856R    NLRP10富含亮氨酸重復結構域蛋白10抗體