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糖類應(yīng)答元件結(jié)合蛋白ChREBP抗體

英文名稱 WBSCR14
中文名稱 糖類應(yīng)答元件結(jié)合蛋白ChREBP抗體
別    名 ChREBP; bHLHd14; Carbohydrate responsive element binding protein; MIO; MLX interacting protein like; Mlx interactor; MLXIPL; MONDOB; WBSCR 14; WBSCR14; Williams Beuren syndrome chromosome region 14; Williams Beuren syndrome chromosome region 14 protein; WS basic helix loop helix leucine zipper protein; WS bHLH; MLXPL_HUMAN.

說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  心血管  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 93kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain. ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of phospho-serine 196.

Function:
Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity).

Subunit:
Binds DNA as a heterodimer with TCFL4/MLX.xy-7025R    Otoraplin纖維細(xì)胞源性蛋白
xy-6724R    OTC鳥氨酸氨基甲酰轉(zhuǎn)移酶抗體
xy-5901R    OS9OS-9蛋白抗體
xy-4147R    Cenexin1精子尾部結(jié)構(gòu)蛋白抗體
xy-5530R    phospho-ODF2(Ser796)磷酸化精子尾部結(jié)構(gòu)蛋白抗體
xy-3687R    OGG18-羥基鳥嘌呤DNA糖基化酶
xy-11629R    OR10J3嗅覺(jué)受體家族10亞基J3抗體
xy-11624R    OR2A4嗅覺(jué)受體家族2亞基4抗體
xy-11628R    OR5P3嗅覺(jué)受體家族5亞基3抗體
xy-9369R    ODF3B外致密纖維蛋白3B抗體
xy-4917R    Osteocalcin骨鈣蛋白/骨鈣素抗體
xy-9061R    ODZ3固生蛋白3抗體
xy-9406R    CT135腫瘤/睪丸抗原135抗體
xy-9407R    OIF骨誘導(dǎo)因子抗體
xy-11203R    OCT6八聚體結(jié)合轉(zhuǎn)錄因子6抗體
xy-11194R    OLIG2少突膠質(zhì)細(xì)胞轉(zhuǎn)錄因子2抗體
xy-0807R    Os05g0477200 protein水稻白葉枯病菌Os05g0477200蛋白抗體
xy-8506R    OSTM1骨硬化病相關(guān)跨膜蛋白1抗體
xy-9915R    Orosomucoid 2類粘蛋白2抗體
xy-0830R    Oct4胚胎干細(xì)胞關(guān)鍵蛋白抗體
xy-0431R    OPG骨保護(hù)蛋白/護(hù)骨素抗體
xy-1077R    OCT2陽(yáng)離子轉(zhuǎn)運(yùn)蛋白2抗體
xy-0019R    osteopontin骨橋蛋白/分泌型磷蛋白1抗體
xy-0026R    osteopontin骨橋蛋白抗體(分泌型磷蛋白1)
xy-1181R    Orexin-A增食欲素A/欲激素A
xy-1110R    Osterix成骨相關(guān)轉(zhuǎn)錄因子抗體
xy-0283R    Ovalbumin雞卵白蛋白/卵清蛋白抗體
xy-1095R    Orexin receptor 1+2丘腦分泌素受體1+2/食欲素受體1+2抗體
xy-1075R    OCT1陽(yáng)離子轉(zhuǎn)運(yùn)器1抗體
xy-1698R    ox-LDL氧化低密度脂蛋白抗體
xy-0470R    Osteocalcin骨鈣蛋白/骨鈣素抗體
xy-13658R    Optineurin視神經(jīng)病變誘導(dǎo)蛋白抗體
xy-5017R    Oct2胚胎干細(xì)胞關(guān)鍵蛋白2抗體
xy-4052R    Oct-1胚胎干細(xì)胞關(guān)鍵蛋白1抗體