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WNT蛋白家族Wnt8b抗體

英文名稱 Wnt8b
中文名稱 WNT蛋白家族Wnt8b抗體
別    名 Protein Wnt-8b; Wingless related MMTV integration site 8b; Wingless type MMTV integration site family, member 8B; Wnt 8b; Wnt8 b; Wnt8b; WNT8B_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Wnt8b
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

Function:
Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.

Subcellular Location:
Secreted

Tissue Specificity:
Expression is restricted to the brain, and more specifically to the forebrain.xy-7595R    PPM1F鈣調(diào)蛋白依賴性蛋白激酶磷酸酶抗體
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xy-11107R    PCDH11X原鈣粘附蛋白11X抗體
xy-11108R    PCDH11Y原鈣粘附蛋白11Y抗體
xy-11109R    PCDH12原鈣粘附蛋白12/血管內(nèi)皮鈣粘蛋白2抗體
xy-11110R    PCDH17原鈣粘附蛋白17抗體
xy-11111R    PCDH1原鈣粘附蛋白1抗體
xy-11115R    PCDHA1原鈣粘附蛋白α1抗體
xy-11117R    PCDHA3原鈣粘附蛋白α3抗體
xy-11118R    PCDHA4原鈣粘附蛋白α4抗體
xy-11119R    PCDHA5原鈣粘附蛋白α5抗體
xy-11120R    PCDHA9原鈣粘附蛋白α9抗體
xy-11121R    PCDHA7原鈣粘附蛋白α7抗體
xy-11122R    PCDHA8原鈣粘附蛋白α8抗體
xy-6285R    PRSS10絲氨酸蛋白酶10抗體
xy-5825R    PCDHA12原鈣粘蛋白12抗體
xy-6293R    Prostatic Acid Phosphatase前列腺酸性磷酸酶抗體
xy-5733R    PAR6缺陷性分配同源物α抗體
xy-5826R    PCDHAC1原鈣粘蛋白1抗體
xy-5814R    Prominin 2造血干細(xì)胞抗原CD133相關(guān)蛋白抗體
xy-6266R    PTK6酪氨酸蛋白激酶6/乳腺腫瘤激酶抗體
xy-5734R    PCGF1表觀抑制因子Polycomb家族成員PCGFl蛋白抗體
xy-11133R    PCDHAC2原鈣粘蛋白介導(dǎo)的PCDHαC2受體抗體
xy-3517M    PAK4小鼠抗p21激活激酶4抗體
xy-7534R    PGC1 beta過氧化物酶體增殖物激活受體γ輔激活子1β抗體
xy-7535R    PGC1 alpha + beta過氧化物酶體增殖物激活受體γ輔激活子1α+β抗體
xy-11788R    Prion protein PrP/CD230朊病毒蛋白CD230抗體
xy-11410R    Progestin Receptor Beta孕激素受體β（MPRβ）抗體
xy-11411R    PTGFR前列腺素F2a受體抗體PGF2αR
xy-6350R    pan methyl Lysine泛甲基賴氨酸抗體