原癌基因wnt7a蛋白抗體 返回列表頁

原癌基因wnt7a蛋白抗體

英文名稱 WNT7A
中文名稱 原癌基因wnt7a蛋白抗體
別    名 Protein Wnt-7a; wnt 7a;Protein Wnt-7a precursor; proto-oncogene wnt7a protein; wingless-type MMTV integration site family, member 7A; WNT7A; WNT7A_HUMAN.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
細(xì)胞定位 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WNT7A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts.

Function:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).

Subunit:
Interacts with PORCN.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.

DISEASE:
Defects in WNT7A are the cause of limb pelvis hypoplasia aplasia syndrome (LPHAS) [MIM:276820]. A syndrome of severe deficiency of the extremities due to hypo- or aplasia of one or more long bones of one or more limbs. Pelvic manifestations include hip dislocation, hypoplastic iliac bone and aplastic pubic bones. Thoracic deformity, unusual facies and genitourinary anomalies can be present.
Defects in WNT7A are a cause of Fuhrmann syndrome (FUHRS) [MIM:228930]; also known as fibular aplasia or hypoplasia femoral bowing and poly- syn- and oligodactyly. Fuhrmann syndrome is a distinct limb-malformation disorder characterized also by various degrees of limb aplasia/hypoplasia and joint dysplasia. 

Similarity:
Belongs to the Wnt family.

Gene ID:
7476

Database links:xy-6370R    p70 S6 kinase alpha核糖體p70 S6蛋白激酶抗體
xy-7094R    p53AIP1p53調(diào)節(jié)凋亡誘導(dǎo)蛋白1抗體
xy-7101R    PTRH2Bcl-2轉(zhuǎn)錄抑制因子1抗體
xy-7099R    PLSCR3磷脂爬行酶3抗體
xy-7634R    PARL骨骼肌細(xì)胞線粒體膜蛋白PARL抗體
xy-7100R    PNPT1多核苷酸磷酸化酶蛋白抗體
xy-6382R    PTK5胃腸道相關(guān)酪氨酸激酶抗體（蛋白酪氨酸激酶5）
xy-6392R    PCNPPEST含核蛋白抗體
xy-3020R    phospho-p53BP1 (Ser25 + Ser29)磷酸化p53結(jié)合蛋白1抗體
xy-3756R    PP1A蛋白磷酸酶2Cα抗體
xy-3744R    Phospho-Paxillin(Tyr31)磷酸化樁蛋白Paxillin抗體
xy-3806R    PGP9.5神經(jīng)細(xì)胞胞漿蛋白9.5抗體（蛋白基因產(chǎn)物9.5）
xy-4024R    phospho-PKA beta(Ser338)磷酸化蛋白激酶Aβ抗體
xy-3963R    PKA R2蛋白激酶A受體2α亞基抗體
xy-4022R    phospho-PKA R2 (Ser96)磷酸化蛋白激酶A受體2α亞基抗體
xy-3964R    PKA gamma蛋白激酶Aγ抗體
xy-3965R    PKA regulatory subunit I beta蛋白激酶受體相關(guān)1β抗體
xy-6466R    PRDM1B淋巴細(xì)胞誘導(dǎo)成熟蛋白1抗體
xy-5179R    phospho-PTPRA(Tyr798)磷酸化酪氨酸磷酸酶α抗體
xy-3969R    PRKAR1蛋白激酶A調(diào)節(jié)亞基a1抗體
xy-5175R    phospho-PTPRA (Ser180)磷酸化酪氨酸磷酸酶α抗體
xy-9039R    PDZD5APDZ結(jié)構(gòu)域PDZK5A蛋白抗體
xy-5423R    PPAP2A磷酸脂磷酸水解酶1抗體
xy-4592R    P14ARF抑癌基因p16/p14/P19抗體
xy-9187R    PTPH1蛋白酪氨酸磷酸酶H1抗體
xy-5587R    phospho-PI 3 Kinase p110 delta (Tyr524)磷酸化磷脂酰肌醇激酶催化亞單位D抗體
xy-5643R    phospho-RAD9(Ser277)磷酸化細(xì)胞周期檢查控制蛋白質(zhì)抗體
xy-7128R    Perforin穿孔素抗體
xy-13674R    PALM3PALM3抗體
xy-5107R    PON1芳香酯酶1(對(duì)氧磷酶)抗體
xy-5108R    PNPO磷酸吡哆醇氧化酶抗體