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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> 信號傳導(dǎo)抑制蛋白WD重復(fù)蛋白2抗體
產(chǎn)品型號
品 牌Abcam
廠商性質(zhì)生產(chǎn)商
所 在 地上海
更新時間:2015-06-05 14:56:25瀏覽次數(shù):182次
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英文名稱 WD SOCS box protein 2
中文名稱 信號傳導(dǎo)抑制蛋白WD重復(fù)蛋白2抗體
別 名 SOCS box containing WD protein SWiP 2; WD 40 repeat containing protein with a SOCS box 2; CS box containing WD protein; SBA2; Swip2; WD repeat and SOCS box containing 2; WD repeat and SOCS box containing protein 2; WD SOCS box protein 2; WSB 2;
說 明 書 0.1ml 0.2ml
研究領(lǐng)域 腫瘤 細胞生物 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) 腫瘤細胞生物標(biāo)志物
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WSB2/WD SOCS box protein 2
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
WSB2 is a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases.
Function:
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Similarity:
Contains 1 SOCS box domain.
Contains 5 WD repeats.
Database links:
UniProtKB/Swiss-Prot: Q9NYS7.1
Important Note:
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