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Wnt1信號(hào)通路蛋白1抗體

英文名稱 WISP1
中文名稱 Wnt1信號(hào)通路蛋白1抗體
別    名 CCN 4; CCN4; WISP 1; WISP 1c; WISP 1i; WISP 1tc; WISP1c; WISP1i; WISP1tc; WNT 1 induced secreted protein 1; Wnt 1 induced secreted protein; WNT 1 inducible signaling pathway protein 1; Wnt 1 signaling pathway protein 1; WNT1 induced secreted protein 1; Wnt1 induced secreted protein; WNT1 inducible signaling pathway protein 1; Wnt1 signaling pathway protein 1; WISP1_HUMAN

說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human WISP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
his gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2011]. xy-1204R    P2Y1P2Y1受體抗體/嘌呤受體抗體
xy-0427R    P311 protein神經(jīng)再生相關(guān)蛋白抗體
xy-0637R    P38 MAPK絲裂原活化蛋白激酶p38α抗體
xy-1069R    proCNP促尿鈉排泄肽前體C抗體
xy-0739R    PAP2c磷脂酸磷酸酶2C抗體
xy-1199R    PAX1配對(duì)盒基因1抗體
xy-1187R    PAX2配對(duì)盒基因2抗體
xy-3520R    PAK2p21激活激酶2抗體
xy-3534R    PLC beta 3磷酯酶Cβ3抗體
xy-3328R    Phospho-PEA15 (Ser104)磷酸化星形膠質(zhì)細(xì)胞PEA15抗體
xy-3329R    Phospho-PEA15(Ser116)磷酸化星形膠質(zhì)細(xì)胞PEA15抗體
xy-1712R    Pan Cytokeratin廣譜細(xì)胞角蛋白PCK抗體
xy-4550R    Pectinesterase果膠酶抗體
xy-9321R    PRPF4PRPF4蛋白抗體
xy-2036R    Penicillin G青霉素G抗體
xy-6976R    Phospholipase C beta 1磷酯酶Cβ1抗體
xy-7619R    PSRC1富含脯氨酸/絲氨酸卷曲螺旋蛋白1抗體
xy-6966R    p47-phoxNADPH氧化酶活化蛋白p47抗體
xy-9349R    Proteasome 19S S7蛋白酶體PRS7抗體
xy-9350R    Proteasome 20S C2蛋白酶體PSMα1抗體
xy-9351R    Proteasome 20S alpha 2蛋白酶體PSMα2抗體
xy-9355R    Proteasome 20S alpha 6蛋白酶體PSMα6抗體
xy-9356R    PSMA7蛋白酶體PSMα7抗體
xy-9612R    PIBF1孕酮誘導(dǎo)阻斷因子1抗體
xy-9623R    PARP16多腺苷二磷酸多聚酶16抗體
xy-9605R    PITX2成對(duì)樣同源結(jié)構(gòu)域轉(zhuǎn)錄因子2抗體
xy-6972R    RNA polymerase IIRNA聚合酶II抗體
xy-1364R    PHLDA1T淋巴細(xì)胞凋亡相關(guān)蛋白TDAG51抗體