液泡蛋白分選蛋白72抗體 返回列表頁

液泡蛋白分選蛋白72抗體

英文名稱 VPS72/YL1
中文名稱 液泡蛋白分選蛋白72抗體
別    名 CFL1; Protein YL 1; RP11-68I18.8; Swc 2; Swc2; TCFL 1; TCFL1; Transcription factor like 1; Vacuolar protein sorting 72 homolog; Vacuolar protein sorting associated protein 72 homolog; VPS 72; YL 1; YL1.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Zebrafish, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human VPS72/YL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

Function:
Could be a DNA-binding transcriptional regulator. May be involved in chromatin modification and remodeling.

Subunit:
Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. Component of a NuA4-related complex which contains EP400, TRRAP/PAF400, SRCAP, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, actin, ACTL6A/BAF53A, VPS72 and YEATS4/GAS41. Also part of a multiprotein complex which contains SRCAP and which binds to H2AFZ/H2AZ.

Similarity:
Belongs to the VPS72/YL1 family.xy-15501R    PCSK4原蛋白轉(zhuǎn)化酶4抗體
xy-4978R    PMCA1細(xì)胞膜鈣ATP酶1抗體
xy-4972R    PCK1磷酸烯醇丙酮酸羧激酶抗體
xy-4966R    PAPOA多聚合酶α抗體
xy-4968R    PAPOG多聚合酶g抗體
xy-11534R    QRFP神經(jīng)內(nèi)分泌肽QRFP抗體
xy-6394R    Quiescin Q6巰基氧化酶1抗體
xy-11668R    QPRT/QAPRTase喹啉酸磷酸核糖基轉(zhuǎn)移酶抗體
xy-11579R    QK1RNA結(jié)合蛋白QK1抗體
xy-11580R    RAI3維甲酸誘導(dǎo)蛋白3抗體
xy-11581R    RAPGEF2Rap鳥嘌呤核苷酸交換因子2抗體
xy-11582R    RAPGEF5/RepacRap鳥嘌呤核苷酸交換因子(GEF)5抗體
xy-11583R    RND2/Rho7Rho家族GTP酶2抗體
xy-11752R    REEP1受體輔助蛋白1抗體
xy-11753R    RNF135環(huán)指蛋白135抗體
xy-11669R    RNF146環(huán)指蛋白146抗體
xy-11783R    Rab5bRAS相關(guān)蛋白R(shí)ab5B抗體
xy-7828R    RINT1胞膜間內(nèi)質(zhì)網(wǎng)調(diào)節(jié)蛋白1抗體
xy-7829R    RMND1減數(shù)分裂同源蛋白1抗體
xy-7845R    RASSF7RAS家族關(guān)聯(lián)結(jié)構(gòu)域蛋白7抗體
xy-6941R    RNF74環(huán)指蛋白74抗體（重組激活基因1）
xy-6960R    RAG2重組激活基因2蛋白抗體
xy-9481R    REEP5受體表達(dá)蛋白5/息肉相關(guān)蛋白抗體
xy-11005R    FAM64A染色體分離調(diào)節(jié)蛋白1抗體
xy-11304R    RFC1復(fù)制激活因子C1抗體
xy-11305R    RFC2復(fù)制激活因子C2抗體
xy-11273R    REAB淋巴細(xì)胞受體相關(guān)蛋白抗體
xy-3023R    phospho-RUNX1 (Ser249)磷酸化急性髓細(xì)胞白血病1蛋白抗體
xy-3551R    RIPK3受體結(jié)合絲氨酸蘇氨酸激酶3抗體
xym-0855M    Insulin (1G11)胰島素單克隆抗體