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液泡蛋白分選蛋白29抗體

英文名稱 VPS29
中文名稱 液泡蛋白分選蛋白29抗體
別    名 DC15; DC7; DKFZp564F0223; FLJ20492; hVPS29; PEP11; PEP11 homolog; Retromer protein; Vacuolar protein sorting 29; Vacuolar protein sorting 29 (yeast homolog); Vacuolar protein sorting 29 (yeast); Vacuolar protein sorting 29 homolog (S. cerevisiae); Vacuolar protein sorting 29 homolog; Vacuolar protein sorting associated protein 29; Vacuolar protein sorting-associated protein 29; Vacuolar sorting protein VPS29/PEP11; Vesicle protein sorting 29; VPS 29; VPS29; VPS29_HUMAN; x 007 protein.

說 明 書 0.2ml  
研究領域 細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Rabbit, Guinea Pig, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
細胞定位 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human VPS29
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]

Function:
Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).

Subcellular Location:
Cytoplasm. Membrane. Endosome membrane.

Tissue Specificity:
Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.xy-9423R    TSPAN16四分子交聯(lián)體16抗體（四旋蛋白）
xy-9426R    TSPAN20四分子交聯(lián)體20抗體（四旋蛋白）
xy-4886R    TREM1髓系細胞觸發(fā)受體1抗體
xy-11177R    Trypsin Inhibitor胰蛋白酶抑制劑抗體
xy-8599R    T2R6味覺感受器蛋白T2R6抗體
xy-8650R    T2R38味覺感受器蛋白T2R38抗體
xy-8729R    TPH25色氨酸羥化酶2抗體
xy-11439R    TXNDC11硫氧還蛋白11抗體
xy-11313R    TUBA4A微管蛋白4α抗體
xy-11310R    DYNLT1動力蛋白輕鏈
xy-11035R    TNFAIP8L2腫瘤壞死因子誘導蛋白8樣蛋白2/TNFα-IP 8L2抗體
xy-11311R    TPOR血小板生成素受體抗體
xy-11183R    TMPRSS5跨膜絲氨酸蛋白酶5抗體
xy-11331R    TBR2脫中胚蛋白抗體
xy-8528R    TPP1細胞生長抑制基因1蛋白抗體
xy-0706R    T4/L-Thyroxine甲狀腺素T4抗體
xy-9852R    TFCP2C轉(zhuǎn)錄因子CP2抗體
xy-9449R    TET2甲基雙加氧酶TET2抗體
xy-1327R    Tenascin C (C terminal)細胞粘合素抗體(C端)腱糖蛋白-C(固生蛋白)抗體
xy-1173R    TNFRSF18糖皮質(zhì)激素誘導腫瘤壞死因子受體抗體
xy-1355R    TANKTANK抗體
xy-0631R    Gamma-taxilin脂多糖相關反應蛋白5/γ-taxilin抗體
xy-8537R    Thymidylate synthase胸苷酸合成酶抗體
xy-0458R    Thioredoxin硫氧還蛋白抗體
xy-1365R    Tsg101腫瘤易感基因101蛋白抗體
xy-9410R    TSPAN1四分子交聯(lián)體1抗體（四旋蛋白）
xy-9411R    TSPAN2四分子交聯(lián)體2抗體（四旋蛋白）
xy-9146R    TTC33TTC33蛋白抗體
xy-9412R    TSPAN3四分子交聯(lián)體3抗體（四旋蛋白）
xy-12067R    TLX2T淋巴細胞白血病同源蛋白2抗體
xy-12068R    TMEM132A跨膜蛋白132A抗體
xy-12069R    TTC21B四聚體多肽蛋白21B抗體
xy-9622R    Tropomyosin原肌球蛋白1抗體
xy-9603R    TEF3轉(zhuǎn)錄增強因子TEF3抗體